Results 181 to 190 of about 262,063 (357)
A critical phantom study of the energy window used for 99mTc quantitative explorations with a ring CZT SPECT system. [PDF]
Seret A, Bernard C.
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Design and application of a realistic and multifunctional retinal phantom for standardizing ophthalmic imaging systems. [PDF]
Lee HJ, Lee TG, Doh I, Lee SW.
europepmc +1 more source
A phantom road experiment reveals traffic noise is an invisible source of habitat degradation
Heidi E. Ware+3 more
semanticscholar +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Hyperparameter-controlled regularized reconstruction method based on object structure and acquisition conditions in SPECT. [PDF]
Minagawa T, Hori K, Hashimoto T.
europepmc +1 more source
A novel physical anthropomorphic breast phantom for 2D and 3D x‐ray imaging
L. Ikejimba+6 more
semanticscholar +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source