Results 211 to 220 of about 335,884 (300)

Patient doses in image-guided radiotherapy: status in Europe for cone-beam CT imaging in the pelvic region. [PDF]

Radiol Oncol
Kansanoja T, Brovchuk S, Vezirovic M, Petrovic B, Amico AG, Sapignoli S, Paiusco M, Ferrari P, Sá AC, Dias AG, Teles P, Siiskonen T.   +11 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Utility of Peripheral Nerve Block in Lower Extremity Amputation. [PDF]

J Pain Res
Onyewu SC, Yanez D, Nnamdi J, Onyewu MC, Effraim PR.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Reoperation and complication rates in acute lower limb amputations due to trauma. [PDF]

Bone Jt Open
Trompeter AJ, Brookes C, Dardak S, Allen E, Cho B, Lohn J, Kolli V.   +6 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

CoMind R1: a time-resolved interferometric optical neuromonitoring system for pulsatile cerebral blood flow measurement at late times-of-flight. [PDF]

Neurophotonics
Parfentyeva V, Behera A, Avtzi S, Tran-Van-Minh A, Etard O, Freer S, Tambe T, Mehmed A, Isufaj A, Goodrich J, Ibrahim Y, Singh N, Darabi S, Villar Sanjurjo P, Malde S, Ali T, Kim Y, Sturniolo S, Ruesch A, Hill DW, Salehi Lashkajani A, Zhang Y, McCarthy P, Hu X, Antrobus A, Maine C, Thackrah M, Valley MT, Crutchley B, Borycki D, Dragojević T, Lindner C, Cooper RJ.   +32 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source