Results 51 to 60 of about 172,482 (290)
, 2021 Work of art in collage, gouache, wooden panel by artist Matthew Johnson as part of a 2021 MFA Exhibition, entitled "Phantom ...
Johnson, Matthew
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Uniformity of Dose Distribution in Target Volume in Radiotherapy Techniques for Breast after Mastectomy. [PDF]
Journal of Advanced Biomedical Sciences, 2013 Background & Objective: Radiotherapy has a very special significance in the treatment of cancer. Beam radiation therapy using photons and electrons produced by a linear accelerator is used extensively in the treatment of breast Cancer.
Sajad Pashton shayesteh +4 more
doaj
International Archives of Allergy and Immunology, 2010 Sensitivity to strong odors has a broad differential diagnosis. A presentation is made of a 60-year-old man with lifelong mild allergic rhinitis and a superimposed 4-year history of sensitivity to smells. He had no response to medical treatments or allergic immunotherapy. His physical examination was unremarkable.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2020 Due to the rapid development and further improvement of radiation treatment technologies oncologists have an opportunity to precisely deliver individual dose distributions to the tumor, minimizing the doses obtained by critical organs and healthy ...
M. N. Piatkevich +2 more
doaj +1 more source
Elucidating the Phantom Phantom
Hypothesis, 2008 Research magnetic resonance imaging (MRI) faces the negative effects of the phantom phantom, a spirit that haunts the MRI system, specifcally targeting inanimate "phantoms" used for imaging in the absence of a willing human. The detrimental effects of the phantom phantom are strongest when frustration is high. Here, given appropriate frustration, it is
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source