Results 181 to 190 of about 94,642 (375)

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

Arthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid, Samuel Kemble, Oladimeji Abudu, Anella Saviano, Christopher Mahony, Jonathan W. Lewis, Thomas A. Nicholson, Anna Schettino, Noemi Marigliano, Kathryn Frost, Jenefa Begum, Alyssa M. Urbanowski, Marion Limo, Rakesh Jha, Sandra Martinez Jarquin, Laleh Pezhman, Abbie E. A. Degan, Amy E. Anderson, Charlotte G. Smith, Armaiti Batki, Holly Adams, Francesco Caso, Raffaele Scarpa, Iain McInnes, Stefan Siebert, Arthur G. Pratt, Andrew Filer, Karim Raza, Adam P. Croft, Myriam Chimen, Felicity de Cogan, G. Ed Rainger, Asif J. Iqbal, Francesco Maione, Helen M. McGettrick   +34 more
wiley   +1 more source

Combined Reconstruction of the Medial Patellofemoral Ligament and the Medial Quadriceps Tendon–Femoral Ligament Using Rectus Femoris Tendon Autograft

Arthroscopy Techniques, EarlyView.
Abstract Patellofemoral instability remains a challenging condition, especially in skeletally immature patients, who are at increased risk of recurrence. The medial patellofemoral ligament has historically been the focus of surgical reconstruction; however, recent anatomic studies have also highlighted the medial quadriceps tendon–femoral ligament as ...
Lokman Kehribar, John P. Fulkerson, Ahmet Emin Okutan   +2 more
wiley   +1 more source

Successful Therapy Of Phantom Pain In The Upper Limb By Blocking The Brachial Plexus

, 2000
GO Adeshina, OM Onujagbe, JA Onaolapo
openalex   +2 more sources

Brachial Plexus Block in Phantom Limb Pain: Interesting, but Limited Clinical Benefit in Chronic Setting [PDF]

, 2012
Michael J. Neil
openalex   +1 more source

Frequency of phantom limb pain, limb sensation and stump pain among amputees

, 2023
Naveed Arshad, Hafiz Muhammad Manan Haider Khan, Khalil Ur Rehman, Muhammad Attique Sadiq, Muhammad Rehman, Nadia Attiq   +5 more
openalex   +2 more sources

Medial Patellofemoral Ligament Reconstruction Using Double Limbed Rectus Femoris Autograft

Arthroscopy Techniques, EarlyView.
Abstract Medial patellofemoral ligament reconstruction is routinely performed when conservative treatment fails and patients present with recurrent patellar dislocations. Most described techniques require fixation or some type of bony procedure on the patella.
Vinicios Barreto Melo, Saulo Santos Blunk, Sérgio Marinho de Gusmão Canuto, Lorran Coque Fonseca, Camilo Partezani Helito, Victor Bezerra de Menezes Monnerat, Pedro Baches Jorge   +6 more
wiley   +1 more source

Role of Potassium Ions Quantum Tunneling in the Pathophysiology of Phantom Limb Pain [PDF]

, 2020
Mustafa Alrabayah, Abdallah Barjas Qaswal, Aiman Suleiman, Lubna Khreesha   +3 more
openalex   +1 more source

Arthroscopic Anterior and Posterior Glenohumeral Capsular Augmentation With Gracilis Allograft

Arthroscopy Techniques, EarlyView.
Abstract Multidirectional instability in patients with connective tissue disorders such as Ehlers‐Danlos syndrome (EDS) is difficult to treat due to poor tissue quality and frequent failure of standard repairs. We describe an arthroscopic technique using gracilis tendon allografts to perform an anterior and posterior capsular augmentation in the ...
Michael D. Maloney, Omkar N. Prabhavalkar, Samantha Levin, Richard Lander, Brett P. Salazar, Sandeep Mannava   +5 more
wiley   +1 more source