Results 71 to 80 of about 23,782 (335)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Phantom limb therapy improves cortical efficiency of the sensorimotor network in a targeted muscle reinnervation amputee: a case report

Frontiers in Neuroscience, 2023
Targeted muscle reinnervation (TMR) surgery involves the coaptation of amputated nerves to nearby motor nerve branches with the purpose of reclosing the neuromuscular loop in order to reduce phantom limb pain. The purpose of this case study was to create
Jordan A. Borrell, Jordan A. Borrell, Arun Karumattu Manattu, Christopher Copeland, Kaitlin Fraser, Andrew D’Ovidio, Zach Granatowicz, Alex C. Lesiak, Sean C. Figy, Jorge M. Zuniga, Jorge M. Zuniga   +10 more
doaj   +1 more source

Mirror Therapy for the Alleviation of Phantom Limb Pain Following Amputation: A literature review [PDF]

, 2011
Introduction: Phantom Limb pain (PLP) affects up to 85% of all patients following an amputation, causing debilitating effects on their quality of life. Mirror Therapy (MT) has been reported to have potential success for the alleviation of PLP.
Timms, J., Carus, Catherine
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Developing core sets for persons following amputation based on the International Classification of Functioning, Disability and Health as a way to specify functioning [PDF]

, 2009
Amputation is a common late stage sequel of peripheral vascular disease and diabetes or a sequel of accidental trauma, civil unrest and landmines. The functional impairments affect many facets of life including but not limited to: Mobility; activities of
Alarcos Cieza, Alberto Esquenazi, Brooks D, Carolina Schiappacasse, Cieza A, Cieza A, Cieza A, Condie E, Dillingham T R, Ephraim P L, Ephraim P L, Ephraim P L, Esquenazi A, Finch E, Friedbert Kohler, Gerold Stucki, Global Lower Extremity Amputation Group, Grill E, Helena Burger, Isakov E, Jan Geertzen, Jensen M P, Kejlaa G H, Kooijman C M, Lee R Y, Legro M W, Lower Extremity Amputation Study Group, Michael P. Dillon, Nehler M R, Nenad Kostanjsek, Rayman G, Robert Steven Kistenberg, Scheuringer M, Schoppen T, Schoppen T, Spichler E RS, Stier-Jarmer M, Stucki G, Stucki G, Stucki G, Stucki G, Stucki G, Taylor S M, Tentolouris N, Thanni L OA TA, Treweek S P, Walsh N E, Wetterhahn K A, Whiteneck G G, Whyte A S, Wildner M, World Health Organisation, Üstün B   +52 more
core   +2 more sources

Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring

Advanced Healthcare Materials, EarlyView.
This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang, Yujin Ahn, Semin Kwon, Tianhao Yu, Yumin Dai, Julia Walsh, Joo Hun Lee, Sang Mok Park, Seul Ah Lee, Murtuza Peerbhai, Chandan K. Sen, Hyowon Lee, Young L. Kim, Hyunjoon Kong, Chi Hwan Lee   +14 more
wiley   +1 more source

The phantom limb [PDF]

, 1951
Thesis (M.D.)—Boston ...
Freed, Murray
core  

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Usefulness of milnacipran in treating phantom limb pain

Neuropsychiatric Disease and Treatment, 2012
Yasuhide Nagoshi,1 Akira Watanabe,1 Saiko Inoue,1 Tomoki Kuroda,2 Mitsuo Nakamura,3 Yoshitake Matsumoto,4 Kenji Fukui31Department of Psychiatry (Psychosomatic Medicine), Kyoto First Red Cross Hospital, Kyoto, Japan; 2Gojouyama Hospital, Nara, Japan ...
Matsumoto Y, Nakamura M, Kuroda T, Inoue S, Watanabe A, Nagoshi Y, Fukui K   +6 more
doaj  

Regenerative Peripheral Nerve Interface Surgery to Treat Chronic Postamputation Pain: A Prospective Study in Major Lower Limb Amputation Patients

Annals of Surgery Open
Objective:. The objective was to assess the postsurgical outcomes of regenerative peripheral nerve interface (RPNI) surgery in a prospective cohort of major lower extremity amputation patients with chronic postamputation pain. Background:.
Jennifer C. Lee, MD, Carrie A. Kubiak, MD, Christine S.W. Best, MD, Jennifer B. Hamill, MPH, Jamie Ki, MS, Hyungjin Myra Kim, ScD, Randy S. Roth, MD, Jeffrey H. Kozlow, MD, Melissa J. Tinney, MD, Michael E. Geisser, MD, Paul S. Cederna, MD, Stephen W.P. Kemp, MD, Theodore A. Kung, MD   +12 more
doaj   +1 more source