Results 81 to 90 of about 15,514 (184)
Anatomical Study of the Retrodural Space of Okada in the Cervical Region: 3D Micro‐CT Findings
Clinical Anatomy, EarlyView.ABSTRACT The retrodural space of Okada (RSO) is a potential space located posterior to the ligamentum flavum. It can complicate epidural injections owing to its communication with the epidural space and facet joints. The purpose of this study was to clarify the anatomical structures of the cervical RSO and adjacent ligamentous tissues in cadavers ...
Tae‐Hyeon Cho +3 more
wiley +1 more source
Clinical Anatomy, EarlyView.ABSTRACT Anatomy instruction is enhanced when students are engaged and interested in course material, and the relevance of the subject matter to their academic success and professional careers is emphasized. We developed a learning activity for a pre‐clinical anatomy course using the clinical skills of inspection and palpation of a cadaver donor to ...
Aysha Alani +4 more
wiley +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Phantom Sensations: What's a Brain to Do? A Critical Review of the Re-mapping Hypothesis [PDF]
, 2018 I will review the most widely held account of phantom sensations; the “re-mapping hypothesis.” According to the re-mapping hypothesis, amputation is followed by significant neural reorganization that, over time, restores the alignment between the brain’s
DeFranco, Daniel
core
ChemMedChem, Accepted Article.The cannabinoid receptor type 2 (CB2R) is overexpressed under pathological conditions. PET is a suitable non‐invasive imaging technique for diagnosing disease states, but requires a radiotracer that binds to CB2R with high affinity and selectivity. Currently, there is no suitable candidate routinely used in the clinics.
Lea Ueberham +4 more
wiley +1 more source
ChemMedChem, Accepted Article.We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi +18 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek +9 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino +3 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot +8 more
wiley +1 more source