Results 91 to 100 of about 2,921 (254)

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

open access: yesAdvanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu   +7 more
wiley   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

open access: yesAdvanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang   +9 more
wiley   +1 more source

The missing pieces: an investigation into the parallels between Charles Bonnet, phantom limb and tinnitus syndromes

open access: yesTherapeutic Advances in Ophthalmology
Charles Bonnet syndrome (CBS) is a condition characterised by visual hallucinations of varying complexity on a background of vision loss. CBS research has gained popularity only in recent decades, despite evidence dating back to 1760.
Kwame A. Baffour-Awuah   +5 more
doaj   +1 more source

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang   +8 more
wiley   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

open access: yesAdvanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner   +14 more
wiley   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

open access: yesAdvanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo   +11 more
wiley   +1 more source

Pulsed radiofrequency of brachial plexus under ultrasound guidance for refractory stump pain: a case report

open access: yesJournal of Pain Research, 2017
Bixin Zheng, Li Song, Hui Liu Department of Pain Management, West China Hospital of Sichuan University, Chengdu, China Abstract: The post-amputation (pain) syndrome, including stump pain, phantom limb sensation, and phantom limb pain is common ...
Zheng B, Song L, Liu H
doaj  

Three new visual methods for generating phantom sensations: case studies in the relief of upper and lower phantom limb pain, and benign essential tremors

open access: gold, 2010
David H. Peterzell   +8 more
openalex   +1 more source

Active Metamaterials with Tunable Shear Nonreciprocity and Nonlinear Dynamics

open access: yesAdvanced Science, EarlyView.
Active gear‐based mechanical metamaterials enable simultaneous control of translational and torsional stiffnesses by 30–100×, break shear reciprocity under positive versus negative loads, broadly tune resonant frequencies, and offer programmable dynamic responses.
Xin Fang, Miao Yu, Dianlong Yu, Li Cheng
wiley   +1 more source

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