Results 101 to 110 of about 87,568 (329)

Multi-Agent Deployment for Visibility Coverage in Polygonal Environments with Holes [PDF]

open access: yes, 2010
This article presents a distributed algorithm for a group of robotic agents with omnidirectional vision to deploy into nonconvex polygonal environments with holes. Agents begin deployment from a common point, possess no prior knowledge of the environment,
Bullo, Francesco   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sound Transmission-Based Elastography Imaging

open access: yesIEEE Access, 2019
Elastography is of great interest in biomechanics and medical imaging due to its nondestructive capability of mapping elasticity of tissues. The elastography framework relies on external excitations which actuate deformation inside an object.
Dongxu Liu   +3 more
doaj   +1 more source

Phantom Maps in the Stable Module Category

open access: yesJournal of Algebra, 1998
The idea of a phantom map appears in homotopy theory; this paper describes an analogous construction for group algebras. Let \(k\) be a field and \(G\) be a finite group. A map of \(kG\)-modules is called projective if it factors through a projective module.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cole Parameter Estimation for Calibrating the Electrical Impedance Tomography System

open access: yesIEEE Access
Impedance measurement inaccuracies and difficulties in modeling the complex electrical properties of biological tissues often compromise the diagnostic reliability of Electrical Impedance Tomography (EIT).
Hoang Nhut Huynh   +6 more
doaj   +1 more source

Comparison of scandium-44 g with other PET radionuclides in pre-clinical PET phantom imaging

open access: yesEJNMMI Physics, 2019
Purpose The decay characteristics of radionuclides in PET studies can impact image reconstruction. 44gSc has been the topic of recent research due to potential theranostic applications and is a promising radiometal for PET imaging.
Simon Ferguson   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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