Results 111 to 120 of about 87,568 (329)
The algebraic chromatic splitting conjecture for Noetherian ring spectra
, 2018 We formulate a version of Hopkins' chromatic splitting conjecture for an arbitrary structured ring spectrum $R$, and prove it whenever $\pi_*R$ is Noetherian.
Barthel, Tobias +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Brazilian Journal of Radiation SciencesInterventional radiology is widely employed; however, the complexity and duration of certain procedures may result in significant radiation exposure to patients.
Eduardo Souza Santos +2 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Application of a quality threshold to improve liver shear wave elastography measurements in free-breathing pediatric patients [PDF]
UltrasonographyPurpose This study assessed the benefits of quality threshold (QT) implementation for liver shear wave elastography (SWE) in children during free breathing.
Jisoo Kim +5 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On phantom maps into suspension spaces
Kyoto Journal of Mathematics, 2003 A phantom map \(f\colon X\to Y\) is a continuous map with the property that the composite \(W\to X\to Y\) is nullhomotopic whenever \(W\) is a finite complex (this is called a phantom map of the second kind by \textit{C. A. McGibbon} [Handbook of algebraic topology, North-Holland, Amsterdam,1209--1257 (1995; Zbl 0867.55013)].
openaire +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SMART (SiMulAtion and ReconsTruction) PET: an efficient PET simulation-reconstruction tool
EJNMMI Physics, 2018 Background Positron-emission tomography (PET) simulators are frequently used for development and performance evaluation of segmentation methods or quantitative uptake metrics. To date, most PET simulation tools are based on Monte Carlo simulations, which
Elisabeth Pfaehler +4 more
doaj +1 more source