Results 131 to 140 of about 87,568 (329)
Phantom maps, SNT-theory, and natural filtrations on lim^1 sets [PDF]
, 2002 Pierre Ghienne
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Enhancing the stability of CT radiomics across different volume of interest sizes using parametric feature maps: a phantom study [PDF]
, 2022 Laura J. Jensen +6 more
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Relative phantom maps and rational homotopy [PDF]
, 2019 Daisuke Kishimoto, Takahiro Matsushita
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Stable suspension order of universal phantom maps and some stably indecomposable loop spaces [PDF]
, 2007 Kouyemon Iriye
openalex +1 more source
Groups of homotopy classes of phantom maps
Algebraic & Geometric Topology, 2018 A map \(f : E \rightarrow F\) of spectra is said to be \textit{phantom} if the composite \(W \mathop{\longrightarrow}\limits^{g} E \mathop{\longrightarrow}\limits^{f} F\) is zero for each finite spectrum \(W\) and each map \(g : W \rightarrow E\).
openaire +3 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source