Results 201 to 210 of about 87,568 (329)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Digital Phantom for MR Spectroscopy Data Simulation. [PDF]

Magn Reson Med
van de Sande DMJ, Gudmundson AT, Murali-Manohar S, Davies-Jenkins CW, Simicic D, Simegn G, Özdemir I, Amirrajab S, Merkofer JP, Zöllner HJ, Oeltzschner G, Edden RAE.   +11 more
europepmc   +1 more source

The Parametric Images of Microbubbles and Tissue Mimicking Phantoms Based on the Nakagami Parameters Map

, 2015
Nardjess Bahbah, H. Djelouah, Ayache Bouakaz   +2 more
openalex   +1 more source

Quantitative prediction of radio frequency induced local heating derived from measured magnetic field maps in magnetic resonance imaging: A phantom validation at 7 T [PDF]

, 2014
Xiaotong Zhang, Pierre‐François Van de Moortele, Jiaen Liu, Sebastian Schmitter, Bin He   +4 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Generalizable preconditioning strategies for MAP PET reconstruction using Poisson likelihood. [PDF]

Front Nucl Med
Colombo MN, Paganoni M, Presotto L.
europepmc   +1 more source

SAR MAP OF GEL PHANTOM IN A 64MHz MRI BIRDCAGE BY FIBER-OPTIC THERMOMETRY AND FDTD SIMULATION

, 2011
Chirag Mukesh Patel
openalex   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Dynamic Transitions for Fast Joint Acquisition and Reconstruction of CEST- Rex$$ {R}_{ex} $$ and T1$$ {T}_1 $$. [PDF]

Magn Reson Med
Huemer M, Stilianu C, Scholand N, Mackner D, Uecker M, Zaiss M, Stollberger R.   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source