Results 41 to 50 of about 19,428 (303)
Induced sensorimotor brain plasticity controls pain in phantom limb patients
Pain in a phantom limb after limb deafferentation may be due to maladaptive sensorimotor representation. Here the authors find that sensorimotor plasticity induced by BMI training with the phantom hand, contrary to expectation, increased pain while ...
Takufumi Yanagisawa+10 more
doaj +1 more source
Experimental neck muscle pain impairs standing balance in humans [PDF]
Impaired postural control has been reported in patients with chronic neck pain of both traumatic and non-traumatic etiologies, but whether painful stimulation of neck muscle per se can affect balance control during quiet standing in humans remains unclear.
arxiv +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu+7 more
wiley +1 more source
Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain
The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom ...
Sandra Preißler+6 more
doaj +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
The prevalence of phantom limb pain is reported to be as high as 85%. In most amputees, the frequency and intensity of pain attacks decrease over the years; however, approximately 5-10% of amputees continue to have severe phantom limb pain. Unfortunately, the current treatment for chronic phantom limb pain is far from satisfactory.
Nikolajsen, Lone+1 more
openaire +5 more sources
Establishment and biological characterization of radioresistant colorectal cancer cell lines
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu+10 more
wiley +1 more source
An Algorithm Approach to Phantom Limb Pain
Jacob Boomgaardt,1 Kovosh Dastan,1 Tiffany Chan,2 Ashley Shilling,2 Alaa Abd-Elsayed,3 Lynn Kohan2 1Department of Physical Medicine and Rehabilitation, University of Virginia, Charlottesville, VA, USA; 2Department of Anesthesiology, University of ...
Boomgaardt J+5 more
doaj
Background: After amputation, phantom limb pain may be produced by the multisensory processes underling the experience of an intact body. Clinical evidence has shown that cold caloric vestibular stimulation may modify the perception of phantom limb pain.
Catalina Aranda-Moreno+5 more
doaj +1 more source
Thermomechanical Assessment of Breast Tumor Subjected to Focused Ultrasound and Interstitial Laser Heating [PDF]
During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of the present study is to determine the effects of nanoparticle mixed tissues under pulsed and continuous heating ...
arxiv