Results 51 to 60 of about 64,540 (344)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Phantom pain [PDF]

, 2016
Almost anyone with a limb amputation experiences phantom sensations. Moreover, the majority of amputees experience pain. This phenomenon is known as ‘Phantom pain’ and is described as the pain felt from a body part, usually a limb, which is no longer ...
Duca, Kristina, Muscat, Richard
core  

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Emerging pharmacotherapy of tinnitus [PDF]

, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen, Azevedo AA, Bahmad FM, Berthold Langguth, Busto U, Courtney KR, Domeisen H, Feder R, Gananca MM, Goebel G, Goodnick PJ, Gresser U, Guitton MJ, Guitton MJ, Hastak SM, Henry JA, Hilton M, Holstein N, House JW, Kuchar DL, Langguth B, Lenarz T, Mahadevan S, Mardini MK, McCabe BF, Melcher JR, Moller AR, Moller AR, Newman CW, Oliver D, Podoshin L, Richard Salvi, Rogawski MA, Roth SH, Schlee W, Shambaugh GE, Shea JJ, Shulman A, Sieghart W, Tandon R, Wei BPC, Williams SH, Willow M, Zapp JJ   +43 more
core   +1 more source

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Robotic-Enhanced Prosthetic Liners for Vibration Therapy: Reducing Phantom Limb Pain in Transfemoral Amputees

Sensors
Phantom limb pain, a common challenge for amputees, lacks effective treatment options. Vibration therapy is a promising non-pharmacologic intervention for reducing pain intensity, but its efficacy in alleviating phantom limb pain requires further ...
Kacey Roehrich, Mary Goldberg, Goeran Fiedler   +2 more
doaj   +1 more source

Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain

Frontiers in Human Neuroscience, 2017
The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom ...
Sandra Preißler, Désirée Thielemann, Caroline Dietrich, Gunther O. Hofmann, Gunther O. Hofmann, Wolfgang H. R. Miltner, Thomas Weiss   +6 more
doaj   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

Risk Factors Analysis of Phantom Limb Pain in Amputees with Malignant Tumors

Journal of Pain Research, 2023
Xiulin Huo,1,2 Peiying Huang,1 Hexuan Di,3 Tianxiao Ma,3 Sufang Jiang,1 Jie Yao,4 Lining Huang1 1Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Anesthesiology,
Huo X, Huang P, Di H, Ma T, Jiang S, Yao J, Huang L   +6 more
doaj  

Stimulation of the Semicircular Canals or the Utricles by Clinical Tests Can Modify the Intensity of Phantom Limb Pain

Frontiers in Neurology, 2019
Background: After amputation, phantom limb pain may be produced by the multisensory processes underling the experience of an intact body. Clinical evidence has shown that cold caloric vestibular stimulation may modify the perception of phantom limb pain.
Catalina Aranda-Moreno, Kathrine Jáuregui-Renaud, Jaime Reyes-Espinosa, Angelina Andrade-Galicia, Ana E. Bastida-Segura, Lourdes G. González Carrazco   +5 more
doaj   +1 more source