Results 51 to 60 of about 2,001,036 (298)

Phantom sensation and quality of life among patients with lower-limb amputations in the region of Juiz de Fora, Minas Gerais: a cross-sectional study

Dementia & Neuropsychologia, 2021
. An amputation is an irreversible event that causes social, psychological, and functional consequences that reduces the quality of life of the amputee. Phantom pain generally is reported by 50 to 80% of amputees.
Víctor de Oliveira Costa, Fabrício Machado Teixeira, Thais Medeiros Lopes, Henrique Pinto Gomide, Patricia Cardoso Clemente, Demóstenes Moreira   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain

Frontiers in Human Neuroscience, 2017
The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom ...
Sandra Preißler, Désirée Thielemann, Caroline Dietrich, Gunther O. Hofmann, Gunther O. Hofmann, Wolfgang H. R. Miltner, Thomas Weiss   +6 more
doaj   +1 more source

Phantom Limb Pain Treated with Duloxetine: A case series

Psychiatry and Clinical Psychopharmacology, 2021
Phantom limb pain (PLP) is a general complaint after amputation which is usually described as burning, tingling, shooting, and cramping. Spontaneous recovery of phantom limb pain generally last many months or years.
Mihriban Dalkiran, Abdullah Genc, Besir Dikmen, Ilknur Yildirim, Senol Turan   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Robotic-Enhanced Prosthetic Liners for Vibration Therapy: Reducing Phantom Limb Pain in Transfemoral Amputees

Sensors
Phantom limb pain, a common challenge for amputees, lacks effective treatment options. Vibration therapy is a promising non-pharmacologic intervention for reducing pain intensity, but its efficacy in alleviating phantom limb pain requires further ...
Kacey Roehrich, Mary Goldberg, Goeran Fiedler   +2 more
doaj   +1 more source

Interference of unilateral lower limb amputation on motor imagery rhythm and remodeling of sensorimotor areas

Frontiers in Human Neuroscience, 2022
PurposeThe effect of sensorimotor stripping on neuroplasticity and motor imagery capacity is unknown, and the physiological mechanisms of post-amputation phantom limb pain (PLP) illness remain to be investigated.Materials and methodsIn this study, an ...
Shaowen Liu, Shaowen Liu, Wenjin Fu, Conghui Wei, Conghui Wei, Fengling Ma, Nanyi Cui, Xinying Shan, Yan Zhang   +8 more
doaj   +1 more source

Relationship of prosthesis ownership and phantom limb pain: results of a survey in 2,383 limb amputees.

Pain, 2020
Phantom limb pain (PLP) accounts for a significant reduction in quality of life and is difficult to treat. Prosthesis use has been shown to negatively co-vary with PLP.
R. Bekrater-Bodmann, I. Reinhard, M. Diers, X. Fuchs, H. Flor   +4 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Ambulatory continuous peripheral nerve blocks to treat postamputation phantom limb pain: a multicenter, randomized, quadruple-masked, placebo-controlled clinical trial

Pain, 2020
Supplemental Digital Content is Available in the Text. A 6-day ambulatory continuous peripheral nerve block reduces phantom limb pain and pain-induced physical and emotional dysfunction for at least 4 weeks after treatment.
B. Ilfeld, Bahareh Khatibi, K. Maheshwari, S. Madison, Wael Ali Sakr Esa, E. Mariano, M. Kent, Steven Hanling, D. Sessler, J. Eisenach, Steven P. Cohen, E. Mascha, C. Ma, J. Padwal, A. Turan   +14 more
semanticscholar   +1 more source