Results 71 to 80 of about 1,869,147 (386)

A computational model unifies apparently contradictory findings concerning phantom pain

open access: yes, 2014
Amputation often leads to painful phantom sensations, whose pathogenesis is still unclear. Supported by experimental findings, an explanatory model has been proposed that identifies maladaptive reorganization of the primary somatosensory cortex (S1) as a
Boström, K. (Kim)   +4 more
core   +2 more sources

Non-invasive brain stimulation techniques for chronic pain [PDF]

open access: yes, 2014
Copyright © 2014 The Cochrane Collaboration.Various devices are available that can electrically stimulate the brain without the need for surgery or any invasive treatment in order to manage chronic pain.
De Souza, LH   +4 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Robotic-Enhanced Prosthetic Liners for Vibration Therapy: Reducing Phantom Limb Pain in Transfemoral Amputees

open access: yesSensors
Phantom limb pain, a common challenge for amputees, lacks effective treatment options. Vibration therapy is a promising non-pharmacologic intervention for reducing pain intensity, but its efficacy in alleviating phantom limb pain requires further ...
Kacey Roehrich   +2 more
doaj   +1 more source

Phantom Limb Pain Treated with Duloxetine: A case series

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Phantom limb pain (PLP) is a general complaint after amputation which is usually described as burning, tingling, shooting, and cramping. Spontaneous recovery of phantom limb pain generally last many months or years.
Mihriban Dalkiran   +4 more
doaj   +1 more source

Sääriamputoitujen henkilöiden kokemuksia aavesäryistä ja niiden hoitomuodoista [PDF]

open access: yes, 2017
Opinnäytetyön tavoitteena oli selvittää sääriamputoitujen henkilöiden kokemuksia aavesäryistä sekä niiden hoitomuodoista. Opinnäytetyötä varten toteutettiin kolme teemahaastattelua, jotka noudattivat laadullisen tutkimuksen periaatteita.
Nyström, Jesse, Schuvalow, Sonja
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain

open access: yesFrontiers in Human Neuroscience, 2017
The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom ...
Sandra Preißler   +6 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

PHANTOM LIMB PAIN: REVIEW OF LITERATURE

open access: yesKhyber Medical University Journal, 2013
Phantom limb pain is described as abnormal sensation (painful or non painful) from an amputated limb. Phantom limb pain is a very common condition in patients undergoing amputation regardless of the cause of amputation.
Fahim Anwar
doaj  

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