Results 91 to 100 of about 223,710 (297)

Advanced quantitative evaluation of PET systems using the ACR phantom and NiftyPET software [PDF]

open access: hybrid, 2022
Paweł Markiewicz   +18 more
openalex   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A phantom for targeted endomyocardial biopsy training [PDF]

open access: green, 2023
Jacqueline Contento   +4 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

HoloInjection: augmented reality support for CT-guided spinal needle injections

open access: yesHealthcare Technology Letters, 2019
The correct placement of needles is decisive for the success of many minimally-invasive interventions and therapies. These needle insertions are usually only guided by radiological imaging and can benefit from additional navigation support.
Florian Heinrich   +4 more
doaj   +1 more source

Ultrasound Phantoms to Protect Patients from Novices

open access: yesThe Korean Journal of Pain, 2016
With the growing use of ultrasound for pain management, we are interested in how to teach and practice ultrasound-guided procedures. Ethically, we should not insert a needle in a patient until after much practice on a phantom.
Y. H. Kim
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

COMPARATIVE DOSIMETRIC STUDY IN CHEST COMPUTED TOMOGRAPHY USING PHANTOMS

open access: yesBrazilian Journal of Radiation Sciences, 2019
The dissemination of Computed Tomography (CT) scan has promoted a significant increase in the absorbed dose by patients due to the diagnosis. Therefore, it is indispensable to improve protocols, seeking smaller doses, without impairing the diagnostic ...
Wadia Aburjaile   +2 more
doaj   +1 more source

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