Results 131 to 140 of about 283,672 (380)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Reference Breast Phantoms for Low-Cost Microwave Imaging
Tehnički Glasnik, 2020 Microwave imaging provides an alternative method for breast cancer screening and the diagnosis of cerebrovascular accidents. Before a surgical operation, the performance of microwave imaging systems should be evaluated on anatomically detailed ...
Emine Avşar Aydin +1 more
doaj
International Archives of Allergy and Immunology, 2010 Sensitivity to strong odors has a broad differential diagnosis. A presentation is made of a 60-year-old man with lifelong mild allergic rhinitis and a superimposed 4-year history of sensitivity to smells. He had no response to medical treatments or allergic immunotherapy. His physical examination was unremarkable.
openaire +2 more sources
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering.
Biomedical Optics Express, 2016 We present an alternative to the conventional approach, phantoms without scattering nanoparticles, where scattering is achieved by the material itself: spherical cavities trapped in a silicone matrix.
M. Wróbel +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
HoloInjection: augmented reality support for CT-guided spinal needle injections
Healthcare Technology Letters, 2019 The correct placement of needles is decisive for the success of many minimally-invasive interventions and therapies. These needle insertions are usually only guided by radiological imaging and can benefit from additional navigation support.
Florian Heinrich +4 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
COMPARATIVE DOSIMETRIC STUDY IN CHEST COMPUTED TOMOGRAPHY USING PHANTOMS
Brazilian Journal of Radiation Sciences, 2019 The dissemination of Computed Tomography (CT) scan has promoted a significant increase in the absorbed dose by patients due to the diagnosis. Therefore, it is indispensable to improve protocols, seeking smaller doses, without impairing the diagnostic ...
Wadia Aburjaile +2 more
doaj +1 more source