Results 31 to 40 of about 1,157 (263)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Special Libraries, February 1951 [PDF]
, 1951 Volume 42, Issue 2https://scholarworks.sjsu.edu/sla_sl_1951/1001/thumbnail ...
Special Libraries Association
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Computer-Aided Design of Pharmaceutical Tablet Formulations [PDF]
Scientia Pharmaceutica, 2010 The formulation of solid oral dosage forms significantly determines the release rate of active pharmaceutical ingredients (APIs). [...]
openaire +1 more source
Old School Catalog 1916-17, Chicago College of Dental Surgery [PDF]
, 1916 https://scholar.valpo.edu/oldschoolcatalogs/1107/thumbnail ...
Valparaiso University
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Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey [PDF]
, 2009 An ethnobotanical survey was conducted on plants used traditionally for the management of tuberculosis in five local government areas of Ogun State, Nigeria, in a bid to document herbs used in the management of tuberculosis with the aim of identifying ...
Ajaiyeoba, E, Ogbole, O
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Microneedle delivery for improved efficacy of antiretroviral and antibiotic drugs [PDF]
, 2012 Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Stauber, Zachary Jason
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