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Active Pharmaceutical Ingredients
2005Introduction. Process Development. Technology Transfer. Plant Design & Construction. Regulatory Requirements. Process Validation. Quality Assurance and Control. Plant Operations. Materials Management.
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Estrogenic activity of pharmaceuticals and pharmaceutical mixtures in a yeast reporter gene system
Reproductive Toxicology, 2006Pharmaceuticals enter aquatic environments in unchanged form or as metabolites. Little is known about their potential hormonal activity, which is of particular interest due to potential long-term effects on fertility and reproduction in aquatic organisms. Moreover, there is a need to assess the combined activity of pharmaceutical mixtures.
Fent K, Escher C, Caminada D
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Precision Active Pharmaceutical Ingredients are the Goal
Future Medicinal Chemistry, 2016Understanding and exploiting molecular mechanisms in biology is central to chemical biology. Chemical biology studies of biological macromolecules are now in a perfect continuum with molecular level and nanomolecular level mechanistic studies involving whole organisms.
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Pharmaceutically active secondary metabolites of microorganisms
Applied Microbiology and Biotechnology, 1999The antibiotics have been useful in our battles against infectious bacteria and fungi for over 50 years. However, many antibiotics are used commercially, or are potentially useful, in medicine for activities other than their antibiotic action. They are used as antitumor agents, immunosuppressive agents, hypocholesterolemic agents, enzyme inhibitors ...
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Ecotoxicological Quantitative Structure–Activity Relationships for Pharmaceuticals
Bulletin of Environmental Contamination and Toxicology, 2007This paper examined active pharmaceutical ingredients (APIs) acute ecotoxicological modes of action (MOA). It was concluded that the vast majority of APIs acute MOA was non-specific narcosis as; 85% out of 59 APIs had an excess toxicity ratio
Sanderson, H., Thomsen, M.
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Pharmaceutical Activity Management. Organization and Regulation of Pharmaceutical Activity. Part II
This educational manual is the second part of “Organization and regulation of pharmaceutical activity” work, where the main issues of organization and regulation of drug provision of the population and medical institutions of the republic are systematically listed for the first time, in particular, information on wholesale and retail sale of drugs ...openaire +1 more source
[Pharmaceutical information activities].
Yakushigaku zasshi, 1996This paper reviewed the progress of the pharmaceutical information activities after the war during fifty years. Activities of the pharmaceutical information organizations, progress of pharmaceutical information tools and techniques, the pharmaceutical information education in universities are described.
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Pharmaceutically active ionic liquids
2017Many pharmaceutical solids can exist in different physical forms including polymorphs, solvates, hydrates and co-crystals. Polymorphism is observed in more than half of all crystalline pharmaceutical drugs. A drug substance can have multiple polymorphs, each exhibiting different properties including solubility, bioavailability, stability, efficacy etc.
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