Results 61 to 70 of about 1,080,879 (306)
Journal of International Medical Research, 2023 Objectives This study evaluated the effect of implementing a hierarchical pharmaceutical service pattern based on the knowledge–attitude–practice (KAP) intervention theory on patients with systemic lupus erythematosus.
Yinhua Gong +4 more
doaj +1 more source
Antibacterial activities of bacteriocins: application in foods and pharmaceuticals [PDF]
Frontiers in Microbiology, 2014 Bacteriocins are a kind of ribosomal synthesized antimicrobial peptides produced by bacteria, which can kill or inhibit bacterial strains closely-related or non-related to produced bacteria, but will not harm the bacteria themselves by specific immunity proteins.
Yang, Shih-Chun +3 more
openaire +3 more sources
Experimental pharmacological research regarding some new quinazolin-4-ones derivatives [PDF]
, 2019 A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied.
Bratu, Mihaela +8 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Matrix Metalloproteinases and Temporomandibular Joint Disorder: A Review of the Literature [PDF]
, 2019 Temporomandibular disorders (TMD) are progressive degenerative disorders that affect the components of the temporomandibular joint (TMJ), characterized by pain and limitations in function.
Almeida, Luis Eduardo +4 more
core +1 more source
Can’t Buy Me Rights! The Contractual Structure of Asymmetrical Inter-firm Collaborations [PDF]
, 2006 The efficient allocation of control rights in inter-firm collaborations is a widely emphasized issue. In this paper, I empirically identify control rights and the allocation of these rights using a unique survey data set on collaborations between ...
Häussler, Carolin
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Prioritizing Pharmaceutical Activities: A Simulation Exercise
The Canadian Journal of Hospital Pharmacy, 2012 New technologies, such as automated repackaging, robotic unit-dose cart-fill systems, and automated dispensing cabinets, have improved the efficiency, effectiveness, and quality of drug distribution systems. In addition, new pharmacy practice models have been introduced in which pharmacists accept responsibility and accountability for managing drug ...
Sophie, Renet +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source