Results 71 to 80 of about 1,080,879 (306)

The Globalization of Innovation: Pharmaceuticals [PDF]

open access: yes, 2008
Analyzes trends in the global pharmaceutical industry, with a focus on intellectual property creation, business relationships, value-chain activity, and opportunities in India and China.
Ben Rissing   +4 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

CONCEPTUAL MODEL OF ECONOMICAL SAFETY MANAGEMENT OF A PHARMACY ORGANIZATION

open access: yesФармация и фармакология (Пятигорск), 2015
Active influence of external environment on pharmaceutical activity, and the inner processes in pharmaceutical organizations may be accompanied with certain threats appearance for economical state of an organization.
D. A. Kuznetsov, E. A. Korzhavykh
doaj   +1 more source

Pharmaceutical Prices and Political Activity [PDF]

open access: yes
Drug prices have been a conspicuous political issue in much of recent history, but no more so than during health care reform debates in 1993 and 1994.
Catherine Wolfram, Sara Fisher Ellison
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Using Authentic Medication Errors to Promote Pharmacy Student Critical Thinking and Active Learning

open access: yesINNOVATIONS in Pharmacy, 2018
Objective: To promote first year (P1) pharmacy students’ awareness of medication error prevention and to support student learning in biomedical and pharmaceutical sciences.
Reza Karimi   +3 more
doaj   +1 more source

Pushing Drugs: Genomics and Genetics, the Pharmaceutical Industry, and the Law of Negligence [PDF]

open access: yes, 2003
This article presents a piece of a larger, ongoing project on the phenomenon of market-driven manufacturing (MDM) and how tort law should address it.
Feldman, Heidi Li
core   +1 more source

Punishing Pharmaceutical Companies for Unlawful Promotion of Approved Drugs: Why the False Claims Act is the Wrong Rx [PDF]

open access: yes, 2008
This article criticizes the shift in focus from correction and compliance to punishment of pharmaceutical companies allegedly violating the Food, Drug, & Cosmetic Act (FD&C Act) prohibitions on unlawful drug promotion.
Girard, Vicki W.
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Pancreatic lipase inhibitory activity of selected pharmaceutical agents

open access: yesActa Pharmaceutica, 2019
Twenty-five structurally diverse compounds have been tested in vitro for their pancreatic lipase (PL) inhibitory activity. Despite the diversity of tested compounds, the relationship comprising structural attributes of the compounds could be established ...
Hamdan Imad I.   +4 more
doaj   +1 more source

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