Results 41 to 50 of about 121,439 (298)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Palliative care services in Australia 2014 [PDF]

, 2014
This is the third in a planned series of annual reports providing a detailed picture of the national response to the palliative care needs of Australians. Summary This report on Australian palliative care services is the third in this series.

core  

Urine Drug Test Interpretation: An Educational Program's Impact on Resident Knowledge and Comfort Level

MedEdPORTAL, 2018
Introduction Following the release of the Centers for Disease Control and Prevention guidelines in 2016, institutions are encouraged to have controlled substance agreements that require the use of drug screens for appropriate opioid prescribing.
Whitney Aultman, Janna Fett, Colleen Lauster, Sarah Muench, Alexandra Halalau   +4 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Community pharmacy wider roles project [PDF]

, 1999
In 1996 the NHS Executive’s Pharmaceutical and Optical Branch invited health authority bids to carry out pilots testing some form of extended role for community pharmacy. In 1997 it funded twelve pilots.
Woodward, J., Ruston, Annmarie, Edmunds, June, Stewart, Alan, Calnan, Michael .W., Colwill, S., Knight, J.   +6 more
core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Palliative care services in Australia 2013 [PDF]

, 2013
This report provides detailed information on the national response to the palliative care needs of Australians. Summary This report on Australian palliative care services is the second in this series.

core  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Access to pharmaceutical professional services: motivations, preferences, barriers, knowledge, and use of ICT among patients in Antioquia

Medicina U.P.B.
Objective: To identify patients’ knowledge and needs regarding pharmaceutical care services in drugstores, pharmacies-drugstores, and outpatient pharmaceutical services in Antioquia, Colombia.Methods: A descriptive cross-sectional study was conducted ...
Raquel Agudelo Guisao, Jaime Andrés Pereañez, Elkyn Johan Granados Vega, Milena Ortiz Rendón, Javier Mauricio Ceballos   +4 more
doaj   +1 more source

Implementation of pharmaceutical care for older adults in the brazilian public health system: a case study and realistic evaluation

BMC Health Services Research, 2020
Background Pharmaceutical care services have been recognized as the most highly regarded professional pharmacy practice model that allows the identification, intervention, and resolution of drug related problems.
Barbara Barros Silva, Claudia Fegadolli
doaj   +1 more source