Pharmaceutical industry - Open Access .click

Results 151 to 160 of about 537,841 (319)

European Journal of Pharmaceutical Sciences, 2016
Christoph, Saal, René, Holm
openaire +2 more sources

The menopause and the Pharmaceutical Industry

Journal of Psychosomatic Obstetrics & Gynecology, 1997
Since 1975, pharmaceutical firms specializing in the endocrine field have made a vigorous attempt to develop a large market in estrogens for the long-term treatment of postmenopausal women. The success of the contraceptive 'pill' had demonstrated the commercial attractiveness of developing products for an essentially healthy population.
openaire +3 more sources

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source

The Value of Failures in Pharmaceutical R&D [PDF]

We build a cumulative innovation model in which both success and failure provide valuable information for future research. To test this learning mechanism, we use a dataset covering outcomes of world-wide R&D projects in the pharmaceutical industry, and ...
Fabio Pammolli +3 more
core

A Practical Method for Synthesizing Iptacopan

Molecules
Iptacopan, the first orally available small-molecule complement factor B inhibitor, was developed by Novartis AG of Switzerland. Iptacopan for the treatment of PNH was just approved by the FDA in December 2023.
Zhiwei Tang +6 more
doaj +1 more source

Project portfolio planning in the pharmaceutical industry -- strategic objectives and quantitative optimization [PDF]

arXiv
Many pharmaceutical companies face concerns with the maintenance of desired revenue levels. Sales forecasts for the current portfolio of products and projects may indicate a decline in revenue as the marketed products approach patent expiry. To counteract the potential downturn in revenue, and to establish revenue growth, an in-flow of new projects ...
arxiv

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu +8 more
wiley +1 more source

Examining the Link Between Price Regulation, Reimportation, and Pharmaceutical R&D Investment [PDF]

This paper examines the link between price regulation and pharmaceutical research and development (R&D) investment. I identify two mechanisms through which price regulation (or re-importation) may exert an influence on R&D: an expected-profit effect and ...
Vernon, John
core +1 more source

Scaffold hopping for discovery of N, N-dibenzylcinnamamide (DBCA) derivatives as novel allosteric GSK-3β inhibitors: Design, synthesis and anti-inflammatory evaluation

Results in Chemistry
Glycogen synthase kinase-3β (GSK-3β) has been identified to promote inflammation and its inhibitors have also been proven to treat some inflammatory-mediated diseases in animal models.
Xinyi Zhang +8 more
doaj

Integrating MLSecOps in the Biotechnology Industry 5.0 [PDF]

arXiv
Biotechnology Industry 5.0 is advancing with the integration of cutting-edge technologies like Machine Learning (ML), the Internet Of Things (IoT), and cloud computing. It is no surprise that an industry that utilizes data from customers and can alter their lives is a target of a variety of attacks.
arxiv

synthesis