Results 211 to 220 of about 546,286 (339)

The Sources of Quality in the Pharmaceutical Industry [PDF]

This paper analyzes the sources of quality of a pharmaceutical product. After identifying eight quality dimensions, a framework of hypothetical sources that contribute the most to shape those dimensions is established.
Dante Tollio, Enrique Yacuzzi, Fernando Martín, Gabriel Vignola, Verónica Mayochi   +4 more
core  

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

Advanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim, Jin Woong Lee, Piper A. Rawding, Mari Iida, Carter Kim, Kourtney L. Kostecki, Michael J. Poellmann, Bridget Crossman, Ashley S. Liu, YoungSoo Kim, Deric L. Wheeler, Seungpyo Hong   +11 more
wiley   +1 more source

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

Different routes the same destination: a comparative study of antitrust regulation for pharmaceutical industry in the United States and China. [PDF]

Front Pharmacol
Weng J, Liu N.
europepmc   +1 more source

Promising R^|^amp;D Targets in Pharmaceutical Industry

, 1994

openalex   +2 more sources

Guidelines for the Development and Validation of Near‐Infrared Spectroscopic Methods in the Pharmaceutical Industry [PDF]

, 2001
Neville W. Broad, P.P. Graham, Perry A. Hailey, Allison Hardy, Steve Holland, Stephen Hughes, David Lee, K.A. Prebble, Neale Salton, Paul Warren, Ken Leiper   +10 more
openalex   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Current trends in pharmaceutical industry: Post -CoVid-19 pandemic effects. [PDF]

Bioinformation
Mohan M, Rajendiran K, Rajaram Y, Balaji S, Cassinadane A.   +4 more
europepmc   +1 more source

Utilization of Genetically Altered Animals in the Pharmaceutical Industry

, 1999
Daniel G. Rudmann, Stephen K. Durham
openalex   +1 more source

Managing the Pharmaceutical Industry—Health System Interface [PDF]

, 2001
Barbara J. Zarowitz, Bruce K. Muma, Peter Coggan, Glenn M. Davis, Gregory L. Barkley   +4 more
openalex   +1 more source