Results 221 to 230 of about 537,841 (319)

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

The evolving role of investigative toxicology in the pharmaceutical industry. [PDF]

open access: yesNat Rev Drug Discov, 2023
Pognan F   +13 more
europepmc   +1 more source

P3HT‐Based Electroactive Films for In Vitro Neuronal Cell Interfacing

open access: yesAdvanced Materials Interfaces, EarlyView.
Reducing the mechanical mismatch between bioelectronic devices and tissue is crucial for enhancing the characteristics of biointerfaces that better mimic the biological tissues. This work investigates the physico‐chemical properties of tunable nanostructured surfaces obtained from a blend of P3HT and MWCNT electroactive polymer.
Paola Campione   +4 more
wiley   +1 more source

Fast Prototyping and Ex Vivo Evaluation of Dissolvable Millineedle Patches Made by Solvent Casting from CO2 Laser Ablated Elastomer Molds

open access: yesAdvanced Materials Interfaces, EarlyView.
CO2 laser ablation, a fast, inexpensive, and reproducible method, is used to create flexible elastomer molds with millimeter‐long cavities for the fabrication of dissolvable polymer needles. Made from PVP, these milli‐needles achieve ≈560 µm penetration into porcine skin, demonstrating their potential for effective transdermal drug delivery.
Matteo Tollemeto   +7 more
wiley   +1 more source

A Systematic Study of Staphylococcus aureus Biofilm Formation on Thiol‐Ene Polymers: Toward the Development of Microfluidic Bacterial Biofilm Models

open access: yesAdvanced Materials Interfaces, EarlyView.
This work presents a systematic characterization of an emerging polymer platform, off‐stoichiometry thiol‐ene, in terms of its ability to support the formation, growth, and metabolic activity of Staphylococcus aureus biofilms. The findings indicate that thiol‐enes promote S.
Jéssica Amorim   +6 more
wiley   +1 more source

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