Results 231 to 240 of about 574,105 (363)

Secondary metabolite biosynthetic gene clusters and microbial diversity as predicted by shotgun metagenomic sequencing approach in hospitals and pharmaceutical industry wastes. [PDF]

Sci Rep
Lema NK, Gemeda MT, Woldesemayat AA.
europepmc   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

An investigation of the potential for and application of life cycle analysis in the pharmaceutical industry

, 2013
Michael J. Raymond
openalex   +1 more source

The influence of the pharmaceutical industry on the development of gonadotrophins and ovarian stimulation protocols in assisted reproductive technologies. [PDF]

Front Endocrinol (Lausanne)
Child T, Bassett R, Howles CM.
europepmc   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Trends analysis and future study of the pharmaceutical industry field: a scoping review. [PDF]

Daru
Bashirynejad M, Soleymani F, Nikfar S, Kebriaeezadeh A, Majdzadeh R, Fatemi B, Zackery A, Zare N.   +7 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Design and Synthesis of Novel Piperidine Urea Derivatives with Neuroprotective Properties

Pharmaceutical Fronts
Jiayi Li, Mengfei Wang, Ling Jiang, Xinyan Peng, Bo Han, Qingwei Zhang   +5 more
doaj   +1 more source

Current trends in pharmaceutical industry: Post -CoVid-19 pandemic effects. [PDF]

Bioinformation
Mohan M, Rajendiran K, Rajaram Y, Balaji S, Cassinadane A.   +4 more
europepmc   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source