Results 281 to 290 of about 537,841 (319)

ROS‐Driven Nanoventilator for MRSA‐Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti‐Inflammation and Immunomodulation

open access: yesAdvanced Science, EarlyView.
A ROS‐driven in situ oxygen supply nanoventilator based on enzyme nanocapsule can convert ROS into O2 through enzyme cascade reaction between SOD and CAT to relieve lung hypoxia, and kill MRSA by releasing vancomycin, which effectively reduces HIF‐1α expression and balances pro‐inflammatory/anti‐inflammatory macrophages ratio, thereby reducing the ...
Zheng Luo   +7 more
wiley   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source
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Offshoring in the Pharmaceutical Industry

Journal of Information Technology Research, 2008
Offshoring has been adopted as a tool for reducing costs and for gaining strategic advantages by financial services, software development, and other competitive industries. For a variety of reasons, the pharmaceutical industry has been slow to take advantage of the benefits that offshoring can provide.
Jason McCoy, Johannes Sarx
openaire   +2 more sources

The Pharmaceutical Industry

2018
Understanding the pharmaceutical industry is a complex mission, requiring a thorough understanding not only of the firms that produce drugs but also of the decision-making process involved in drug selection for patients, the role of insurance and other third-party payers, and the substantial role of government in monitoring and regulating many aspects ...
Z. John Lu, Stuart O. Schweitzer
openaire   +2 more sources

Pharmacogenetics and the Pharmaceutical Industry

Current Pharmaceutical Design, 2010
The detailed knowledge of the human genome has not fulfilled its promise as yet. It seems fair to say that we are far from treating existing diseases by therapeutic interventions developed on the basis of genetic knowledge. However, pharmacogenetics has shown to be useful in improving our understanding of pharmacotherapy.
Jan A. M. Raaijmakers   +2 more
openaire   +4 more sources

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