Results 301 to 310 of about 546,286 (339)

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

The Pharmaceutical Industry in 2023: An Analysis of FDA Drug Approvals from the Perspective of Molecules. [PDF]

Molecules
de la Torre BG, Albericio F.
europepmc   +1 more source

The Evolving Pharmaceutical Industry [PDF]

, 2009
Couto, Joe, PharmD, MBA
core   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Cross-sectional analysis of financial relationships between board certified allergists and the pharmaceutical industry in Japan. [PDF]

BMC Med Ethics
Murayama A, Senoo Y.
europepmc   +1 more source

P3HT‐Based Electroactive Films for In Vitro Neuronal Cell Interfacing

Advanced Materials Interfaces, EarlyView.
Reducing the mechanical mismatch between bioelectronic devices and tissue is crucial for enhancing the characteristics of biointerfaces that better mimic the biological tissues. This work investigates the physico‐chemical properties of tunable nanostructured surfaces obtained from a blend of P3HT and MWCNT electroactive polymer.
Paola Campione, Claudia Latte Bovio, Giovanna Calabrese, Francesca Santoro, Grazia Maria Lucia Messina   +4 more
wiley   +1 more source

Utilising Endogenous Biomarkers in Drug Development to Streamline the Assessment of Drug-Drug Interactions Mediated by Renal Transporters: A Pharmaceutical Industry Perspective. [PDF]

Clin Pharmacokinet
Choi HJ, Madari S, Huang F.
europepmc   +1 more source

Cross-sectional analysis of pharmaceutical industry payments to authors of clinical practice guidelines for bipolar disorder and major depressive disorder in Japan. [PDF]

BMJ Open
Murayama A, Kugo H, Senoo Y.
europepmc   +1 more source

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The view of the pharmaceutical industry

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994
Rhône-Poulenc Rorer has committed itself to the development of artemether because we believe the drug will be of considerable benefit to sufferers from severe falciparum malaria, and because it is a stable, effective and economical compound that can be given by intramuscular injection.
Gilles Roche, Jean-Pierre Helenport
openaire   +2 more sources