Results 141 to 150 of about 3,602,513 (298)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Building an Intelligent Cardiovascular System Platform: Embedding Artificial Intelligence across All Facets of Cardiovascular Medicine

Advanced Intelligent Systems, EarlyView.
This paper presents an integrated AI‐driven cardiovascular platform unifying multimodal data, predictive analytics, and real‐time monitoring. It demonstrates how artificial intelligence—from deep learning to federated learning—enables early diagnosis, precision treatment, and personalized rehabilitation across the full disease lifecycle, promoting a ...
Mowei Kong, Xingwei Zhao, Qiuting Li, Yang Yu, Chunxiang Zhang   +4 more
wiley   +1 more source

Pharmaceutical Distribution Market Channels in Poland

Contemporary Economics, 2009
Distribution on the pharmaceutical market in Poland is interesting and the most difficult sphere to manage. Numerous varied and specialized companies operating on the market cause that the processes of choosing middlemen in distribution channels are very
Agnieszka Woś
doaj  

Comparing Profiles of Mental Illness and Positive Mental Health Between Injured Workers and the General Working Population in Ontario

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Mental illness (MI) is prevalent among workers with work‐related injury. However, complete mental health includes both MI and positive mental health (PMH). To better understand differences in prevalence, this study compared MI and PMH profiles among injured Ontario workers to a representative sample of the general Ontario working ...
Kathleen G. Dobson, Yu‐Chun Chien, Nancy Carnide, Peter M. Smith, Cameron A. Mustard   +4 more
wiley   +1 more source

Owning Home, Finding Belonging: Relational Meanings of Homeownership for Migrant Healthcare Workers in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT Migrant healthcare workers in Australia find themselves at the centre of three intersecting concerns, often presented as ‘crises’ in contemporary discourse: the ‘care crisis’, the ‘housing crisis’ and the ‘migration crisis.’ Yet their own perspectives on these issues are rarely foregrounded. This paper explores the role of homeownership in the
Leah Williams Veazey
wiley   +1 more source

Healthcare Resource Utilization and Cost After Temperature‐Controlled Radiofrequency Treatment of Nasal Airway Obstruction: A Real‐World Longitudinal Claims Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Nasal airway obstruction (NAO) is prevalent with substantial health and quality of life burdens. Nasal valve collapse (NVC) is one structural cause of NAO. Temperature‐controlled radiofrequency (TCRF) nasal valve remodeling offers an alternative to invasive surgery.
David W. Kennedy, Gavin Setzen, Ashleigh A. Halderman, Kevin C. Welch, Bobby Tajudeen, Gary M. Owens, Paul J. Niklewski, Masayoshi Takashima   +7 more
wiley   +1 more source

Medicaid Coverage and Utilization for Novel Therapies for Chronic Rhinosinusitis With Nasal Polyposis

International Forum of Allergy &Rhinology, EarlyView.
Key Points Most state Medicaid programs granted omalizumab (91.4%) and dupilumab (59.5%) preferred drug status. Omalizumab was the most commonly prescribed therapy among Medicaid patients between 2015 and2024.
Eric R. Ramos, Sriram Satyavolu, Ashley L. Miller, George A. Scangas, Zachary M. Soler, Rodney J. Schlosser, Yufan Lin, Vinay K. Rathi   +7 more
wiley   +1 more source

The Brazilian private pharmaceutical market after the first ten years of the generics law. [PDF]

J Pharm Policy Pract, 2019
Bertoldi AD, Wagner AK, Emmerick ICM, Chaves LA, Stephens P, Ross-Degnan D.   +5 more
europepmc   +1 more source

Preparation of Pectin Aerogels From Flaxseed and Evaluation of Their Potential as Hemostatic Agents: Water Absorption Characteristics

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Flaxseed has been used extensively to extract flaxseed oil and drugs used for breast cancer treatment. Flaxseed contains a considerable amount of pectin in addition. We extracted pectin from flaxseed and prepared pectin aerogels by the steps of de‐esterification, gelation, solvent exchange and supercritical CO2 drying.
Jin‐A Choe, Hyon‐Tae Pak, Kwang‐Myong Cha, Song‐Su Ma, Chol‐Ung Kim, Yong‐Son Rim   +5 more
wiley   +1 more source