Results 181 to 190 of about 1,148,410 (327)

Mapping the TNFR2-targeting antibody patent landscape: Insights from macro trends to structural signatures. [PDF]

Hum Vaccin Immunother
Chen S, Chen Y, Zhang Y, Yao G, Cai H, Chen X, Hu Y.   +6 more
europepmc   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

The impact of patent activity on idiosyncratic volatility in U.S. pharmaceutical companies. [PDF]

PLoS One
Atilgan E, Türkmen Ceylan FB, Doruk ÖT, Ertuğrul HM, Barak AY.   +4 more
europepmc   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

HER2 Protein Overexpression, mRNA Expression, and DNA Amplification Across Solid Tumors: Comparison of Next-Generation Sequencing-Based Assays With Immunohistochemistry. [PDF]

JCO Precis Oncol
Nagamine M, Fujisawa T, Sakamoto N, Nakamura Y, Kadowaki S, Ueno M, Boku S, Komatsu Y, Oki E, Makiyama A, Nonomura N, Morizane C, Watari H, Okano S, Iwata H, Namikawa K, Hatanaka Y, Hatanaka KC, Taguchi K, Spetzler D, Radovich M, Magee D, Yoshino T, Oberley M, Kuwata T.   +24 more
europepmc   +1 more source

Questioning the Frequency and Wisdom of Compulsory Licensing for Pharmaceutical Patents

, 2010
Richard, Epsteint, F. S. Kieffft
semanticscholar   +1 more source

Patent protection of pharmaceuticals.

Acta poloniae pharmaceutica, 2001
Patenting of biologically active compounds by academic institutions is discussed, with emphasis on patents for already known compounds.
openaire   +1 more source

Facilitating Expedited Drug Approval– the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, Accepted Article.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

From Waste to Value: Conversion of Calcium Sulfate to Vaterite via Carbon Capture and Storage

Advanced Functional Materials, EarlyView.
This study introduces a new concept for carbon management that relies on the carbonation of industrial gypsum waste and yields phase‐pure vaterite at ambient conditions without any additives. The obtained vaterite is further shown to be a reactive material that develops compressive strength in aqueous suspensions like conventional cements.
Carlos Pimentel, German Montes‐Hernández, Pablo Almarza‐Cifuentes, Matthias Kellermeier, Alexander E.S. Van Driessche   +4 more
wiley   +1 more source

Patent Landscape of Fiber-Based Fabrication Technologies for Functional Biomaterials: Electrospinning, Forcespinning^® and Melt Electrowriting in Tissue Engineering and Drug Delivery (2020 to 2024). [PDF]

J Funct Biomater
Sattler AM, Rodriguez-Salvador M, Vazquez-Armendariz J, Tejeda Alejandre R.   +3 more
europepmc   +1 more source