Results 41 to 50 of about 1,148,410 (327)
Public and Private International Law Bulletin, 2021 Vaccine nationalism is an obstacle to combating the global COVID-19 pandemic. Since the production of COVID-19 vaccines is still insufficient to meet the needs of the world population, developed countries primarily purchase them for their populations ...
Meltem Sarıbeyoğlu Skalar
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
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Patents and licensing in pharmaceutical industry [PDF]
Makedonsko Farmacevtski Bilten, 2005 Intellectual property rights (IPR) have been defined as ideas, inventions, and creative expressions based on which there is a public willingness to bestow the status of property.
Katerina Ancevska Netkovska +3 more
doaj
Brexit – The Consequences for Pharmaceutical Patents and Supplementary Protection Certificates
British Journal of Pharmacy, 2021 Now that the UK has left the EU, and the transition period following this departure is over, we have a clearer view on the implications of Brexit on intellectual property rights and the consequences for UK based pharmaceutical companies. Although little
Harry Melville O'Brien +2 more
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The Value of Failures in Pharmaceutical R&D [PDF]
, 2012 We build a cumulative innovation model in which both success and failure provide valuable information for future research. To test this learning mechanism, we use a dataset covering outcomes of world-wide R&D projects in the pharmaceutical industry, and ...
Chiou, Jing-Yuan +3 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Case Law: A Review of Selected Pharmaceutical Patents in the UK Courts during 2021
British Journal of Pharmacy, 2022 Patents lie at the interface between technology and law. This review provides a summary of four high-profile cases from 2021 in which patents in the pharmaceutical or medical space were litigated in the UK Courts.
Sarah-Jane Crawford +2 more
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Pharmaceutical Patents in Developing Nations: Parallel Importation and the Doctrine of Exhaustion
, 2014 This article examines the impact of parallel importation and the doctrine of patent exhaustion on access to pharmaceutical products in developing nations around the world. Parallel importation is of particular relevance to developing countries given that
Sarah McKeith
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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