Results 101 to 110 of about 1,517,347 (329)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Implementation of patient prioritisation tools: impact on integrated pharmaceutical care provision
International Journal of Integrated Care, 2019 Introduction: The Scottish Government’s ambition aims for people to live as long as possible at home or in a homely setting. The projected population increase aged 70+ is 55% by 2035 in [removed] Scottish region.
Pamela Mills, Katie MacLure
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The Influence of the Andean Intellectual Property Regime on Access to Medicines in Latin America [PDF]
, 2014 This chapter is a contribution to Balancing Wealth and Health: Global Administrative Law and the Battle over Intellectual Property and Access to Medicines in Latin America, Rochelle Dreyfuss & César Rodríguez-Garavito, eds.
Alter, Karen J., Helfer, Laurence R.
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Vestnik Dermatologii i Venerologii, 2018 The main directions of modernisation of the pharmaceutical care provision of the population of the Russian Federation are systematised based on the results of the analysis of normative legal acts.
A. A. Martynov +3 more
doaj +1 more source
The relationship of drug reimbursement with the price and the quality of pharmaceutical innovations [PDF]
, 2005 This paper studies the strategic interaction between pharmaceutical firms' pricing decisions and government agencies' reimbursement decisions which discriminate between patients by giving reimbursement rights to patients for whom the drug is most ...
García-Alonso, M. D. C. +1 more
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
RUDN Journal of Medicine, 2013 The need to improve the quality of pharmaceutical care to patients of chronic obstructive pulmonary disease (COPD) require a comprehensive pharmaceutical research.
N O Karabintseva, M P Boyko
doaj
Фармация и фармакология (Пятигорск), 2018 The importance of the pharmaceutical safety of the palliative care system, good timing of its delivery, accessibility and quality have been actively discussed in the professional environment only for the latest 4–5 years.
I. A. Tueva +4 more
doaj +1 more source