Results 111 to 120 of about 1,040,359 (356)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Role of immune-pineal axis in neurodegenerative diseases, unraveling novel hybrid dark hormone therapies

open access: yesHeliyon, 2019
The anti-oxidant effects of melatonin and the immune-pineal axis are well established. However, how they play a role in the pathogenesis of neurodegenerative diseases is not well elucidated.
Nitya Beriwal   +3 more
doaj   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

open access: yesFEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita   +3 more
wiley   +1 more source

Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice

open access: yesHeliyon, 2017
The utilisation of nanoparticles as the means of targeted delivery of therapeutics and/or imaging agents could greatly enhance the specific transport of biologically active payloads to target tissues while avoiding or reducing undesired side-effects.
Ali Kermanizadeh   +4 more
doaj   +1 more source

Analysis on the evolution and governance of the biotechnology industry of China [PDF]

open access: yes, 2007
The past twenty years have witnessed the high-speed growth of China’s biotechnology industry, and this presents an excellent opportunity to examine the changes that have taken place, especially, to carry out overall evaluation and governance analysis ...
Hong, J.   +3 more
core   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Technology Development in Transition - The Case of Hungarian Industry - [PDF]

open access: yes
The reform of 1989 exposed Hungarian industry to foreign competition and confronted it to the loss of the vast and undemanding COMECON market, the withdrawal of public support and the need for privatisation.
Henny Romijn
core  

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Reimagining Your Rx [PDF]

open access: yes, 2016
Your future prescriptions might be manufactured in a portable factory – or even be produced by your body itself. Dr. Thomas Roper, director of pharmaceutical engineering in VCU’s Department of Chemical & Life Science Engineering, says the goal is to ...
Jones, Rebecca
core   +1 more source

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