Results 111 to 120 of about 1,067,890 (357)

Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice

Heliyon, 2017
The utilisation of nanoparticles as the means of targeted delivery of therapeutics and/or imaging agents could greatly enhance the specific transport of biologically active payloads to target tissues while avoiding or reducing undesired side-effects.
Ali Kermanizadeh, Nicklas R. Jacobsen, Martin Roursgaard, Steffen Loft, Peter Møller   +4 more
doaj   +1 more source

Jurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical Pharmacy

, 2021
Daftar Isi
openalex   +1 more source

The Future of Drug Development: The Economics of Pharmacogenomics [PDF]

This paper models how the evolving field of pharmacogenomics (PG), which is the science of using genomic markers to predict drug response, may impact drug development times, attrition rates, costs, and the future returns to research and development (R&D).
John A. Vernon, W. Keener Hughen
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Pharmaceutical Regulatory Science

International Journal of Pharmaceutical Research and Applications
TitlePharmaceutical Regulatory Science Authors / Editors Editor: Dr. Ravi Shankar Tripathi Co-Editor: Dr. Pravin Badhe Contributing Authors: Sushmita Hiremath; Nikhil Gawas; Bono Naga Sudha; Thokala Ujwala Reddy; Kanchanam AshaDeepthi; Shaik Shabana; Dr. Vivek R. Mallurwar; Reema Sanghvi; Dr.
Dr. Ravi Shankar Tripathi, Sushmita Hiremath, Nikhil Gawas, Bono Naga Sudha, Thokala Ujwala Reddy, Kanchanam AshaDeepthi, Shaik Shabana, Dr. Vivek R. Mallurwar, Reema Sanghvi, Dr. Sivakumar Kullampalayam Krishnasamy., Dr. Abinaya Mouralidasse, Yarra Sai Phanindra, Mrs. Kandregula Kesava Uma Maheswari   +1 more
openaire   +2 more sources

Availability, Uniqueness and Perceived Value of Bachelor of Science in Pharmaceutical Sciences (BSPS) Programs in the United States [PDF]

, 2013
Rabaa M. Al‐Rousan, Fadi M. Alkhateeb, Michael A. Veronin, David A. Latif, Marea Dodd   +4 more
openalex   +1 more source

Technology Development in Transition - The Case of Hungarian Industry - [PDF]

The reform of 1989 exposed Hungarian industry to foreign competition and confronted it to the loss of the vast and undemanding COMECON market, the withdrawal of public support and the need for privatisation.
Henny Romijn
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Role of in silico Drug Design in Pharmaceutical Sciences

, 2022
Rainul Islam, Sumit Maji, Souparna Kabiraj, Umme Habib, Rohan Pal, Somenath Bhattacharya, Soumallya Chakraborty, Arin Bhattacharjee   +7 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source