Results 1 to 10 of about 55,599 (265)

Intellectual property and access to medicines: mapping public attitudes toward pharmaceuticals during the United States-Mexico-Canada Agreement (USMCA) negotiation process

Globalization and Health, 2021
Background Transparency and accountability are essential components at all stages of the trade negotiation process. This study evaluates the extent to which these principles were upheld in the United States’ public consultation process during the ...
Anna S. Y. Wong, Clarke B. Cole, Jillian C. Kohler   +2 more
doaj   +1 more source

Enantioselective Box Behenken Optimized HPLC-DAD Method for the Simultaneous Estimation of Alogliptin Enantiomorphs in Pharmaceutical For mulations and their Pharmacokinetic Study in Rat Plasma [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: A stereoselective high performance liquid chromatographic analytical method withphotodiode array detector was developed and validated as per the International Conferenceon Harmonization (ICH) guidelines for the determination of alogliptin (ALO ...
Ravi Kant, Ramesh Babu Bodla, Rubina Bhutani, Garima Kapoor   +3 more
doaj   +1 more source

Effect of Deep Eutectic System (DES) on Oral Bioavailability of Celecoxib: In Silico, In Vitro, and In Vivo Study

Pharmaceutics, 2023
Different deep eutectic systems (DES) of choline chloride (CC)–urea (UA) (1:2), CC–glycerol (GLY) (1:2), CC–malonic acid (MA) (1:1), and CC–ascorbic acid (AA) (2:1) were generated and characterized by polarized light microscope (PLM) and Fourier ...
Soumalya Chakraborty, Rohit Y. Sathe, Jaydeep H. Chormale, Ashish Dangi, Prasad V. Bharatam, Arvind K. Bansal   +5 more
doaj   +1 more source

Medicine donations: a review of policies and practices

Globalization and Health, 2023
Background To help promote the effective delivery of drug donations, the World Health Organization (WHO) developed the Guidelines for Medicine Donations.
Hannah Permaul Flores, Jillian C. Kohler, Deirdre Dimancesco, Anna Wong, Joel Lexchin   +4 more
doaj   +1 more source

Comparative studies of two vegetal extracts from Stokesia laevis and Geranium pratense: polyphenol profile, cytotoxic effect and antiproliferative activity

Open Chemistry, 2020
The localization of frontier molecular orbitals (FMOs) for LUTEOLIN: HOMO (the highest occupied molecular orbital) and LUMO (the lowest unoccupied molecular orbital).
Pirvu Lucia, Neagu Georgeta, Terchescu Iulian, Albu Bujor, Stefaniu Amalia   +4 more
doaj   +1 more source

Hepatoprotective agent tethered isoniazid for the treatment of drug-induced hepatotoxicity: Synthesis, biochemical and histopathological evaluation

Toxicology Reports, 2014
The aim of the study was to investigate the protective effect of isoniazid–curcumin conjugate (INH–CRM) in INH-induced hepatic injury by biochemical analysis and histology examination of liver in Wistar rats.
Charan Singh, Laxmikant Jodave, Tara Datt Bhatt, Manjinder Singh Gill, Sarasija Suresh   +4 more
doaj   +1 more source

Production of mycophenolic acid by Penicillium brevicompactum—A comparison of two methods of optimization

Biotechnology Reports, 2016
Production of mycophenolic acid (MPA) by submerged fermentation using the microfungus Penicillium brevicompactum MTCC 8010 is reported here. Screening experiments were used to identify: the suitable media composition; the optimal initial pH; and the ...
Gopal Patel, Mahesh D. Patil, Surbhi Soni, Taresh P. Khobragade, Yusuf Chisti, Uttam Chand Banerjee   +5 more
doaj   +1 more source

Free Radical Scavenging and Antioxidant Activity of Silver Nanoparticles Synthesized from Flower Extract of Rhododendron dauricum

Nano Biomedicine and Engineering, 2012
A simple and efficient eco-friendly approach for the biosynthesis of stable, monodisperse silver nanoparticles (AgNPs) using Rhododendron dauricum flower extract is described.
Amit Kumar Mittal, Abhishek Kaler, Uttam Chand Banerjee   +2 more
doaj   +1 more source

Big Pharma, Big Business [PDF]

Ovidius University Annals: Economic Sciences Series, 2021
Since their birth, human beings have tried to preserve their health in a good condition for as long as it is possible during their life, especially in modern times. The result was not only the appearance and development of the healthcare systems all over
Sorin-George Toma, Stefan Catana
doaj  

Use of response surface method for maximizing the production of arginine deiminase by Pseudomonas putida

Biotechnology Reports, 2016
Statistically designed experiments were used to optimize the production of arginine deiminase (ADI) by Pseudomonas putida KT2440 in batch culture. A Plackett-Burman design involving eleven factors showed that ADI production was most influenced by the ...
Mahesh D. Patil, Kiran D. Shinde, Gopal Patel, Yusuf Chisti, Uttam Chand Banerjee   +4 more
doaj   +1 more source