Results 71 to 80 of about 6,027,899 (340)
RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington’s Disease
Molecular Therapy: Nucleic Acids, 2018 Huntington’s disease (HD) is associated with the misfolding and aggregation of mutant huntingtin harboring an elongated polyglutamine stretch at its N terminus. A distinguishing pathological hallmark of HD is mitochondrial dysfunction.
Kinjal A. Patel +2 more
doaj +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 The aim of the paper is to elucidate the genesis and early development of the national pharmaceutical legislation on the territory of modern Ukraine between IX and early XX centuries taking into account historical and legal aspects.
O. H. Aleksieiev
doaj +1 more source
Innovations Through Mergers and Acquisitions in the Pharmaceutical Sector
Technological Innovations for Sustainability and Business Growth, 2020 Pharmaceutical firms have a noteworthy contribution in SDGs (Sustainable development goals). Their unceasing innovation of low-cost medicines and discovery of lifesaving drugs can assist in achieving the SDG 3 (good health and well-being).
Abdul Wajid, Kashif Khan, Harish Handa
semanticscholar +1 more source
A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space
Advanced Materials Technologies, EarlyView.Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch +7 more
wiley +1 more source
Analysis of Flavonoids and Iridoids in by HPLC-PDA and Method Validation
Natural Product Communications, 2013 The leaves of Vitex negundo have been reported to contain various bioactive constituents including iridoids and flavonoids. This is the first report on the simultaneous determination of iridoids and flavonoids by HPLC in three different samples of V ...
Somendu K. Roy +4 more
doaj +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
ComputersThe invoicing process is critical to the financial management of organizations. However, modeling this process presents challenges such as data updating, information availability, and aligning planned activities with the actual execution of the process ...
Jhon Wilder Sanchez-Obando +2 more
doaj +1 more source
Impact of Managerial Coaching on Employee Performance and Organizational Citizenship Behavior: Intervening Role of Thriving at Work [PDF]
Pakistan Journal of Commerce and Social Sciences, 2017 A thorough probe into managerial coaching effectiveness is rare in the literature. To fill this research gap, this study examines the relationship of managerial coaching and employees’ performance more profoundly.
Basharat Raza (Corresponding author)
doaj
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Evaluation of incentives for R&D in the pharmaceutical industry with applications for neglected diseases [PDF]
, 2011 PhDThis thesis is concerned with the development of incentives for pharmaceutical R&D, specifically for neglected diseases. The following approaches are adopted.
Trushin, Eshref
core +4 more sources