Results 221 to 230 of about 474,657 (298)
Advanced Intelligent Discovery, EarlyView.This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee +3 more
wiley +1 more source
Management of pharmaceutical services in the Brazilian primary health care. [PDF]
Rev Saude Publica, 2017 Gerlack LF +12 more
europepmc +1 more source
Unlocking Value added services in Bio-Pharmaceutical Industry [PDF]
, 2016 Carrasco, Raul, Panda, Swagat Kumar
core
Advanced Intelligent Discovery, EarlyView.This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.This study reveals that sampling strategy (i.e., sampling size and approach) is a foundational prerequisite for building accurate and generalizable AI models in peptide discovery. Reaching a threshold of 7.5% of the total tetrapeptide sequence space was essential to ensure reliable predictions.
Meiru Yan +3 more
wiley +1 more source
Characterization of the institutionalization of pharmaceutical services in Brazilian primary health care. [PDF]
Rev Saude Publica, 2017 Souza GS +12 more
europepmc +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Regular access and adherence to medications of the specialized component of pharmaceutical services. [PDF]
Rev Saude Publica, 2017 Fritzen JS, Motter FR, Paniz VMV.
europepmc +1 more source
The Intraenterprise Conspiracy Doctrin and the Pharmaceutical Benefit Management Industry: A Poposed Exception to the Copperweld Holding [PDF]
, 2011 Timm, Ruth Barber
core +2 more sources
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Advanced Intelligent Discovery, EarlyView.Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source