Results 291 to 300 of about 6,007,608 (352)

Bacillus Coagulans Unique IS2 Improves Stool Characteristics In Healthy Adults With Infrequent Bowel Movements: A Randomized, Double-Blind, Placebo-Controlled Trial

open access: yesCurrent Developments in Nutrition
Leila M Shinn   +10 more
doaj  

Practical Considerations of FDA’s CLAP List to Support Testing of Extractables for Pharmaceuticals and Medical Devices

open access: yesACS Omega
Megan Flohl   +5 more
doaj   +1 more source

Cooperative Ammonia Formation Catalyzed by Molybdenum and Samarium Complexes

open access: yesAngewandte Chemie International Edition, Accepted Article.
A series of novel samarium complexes bearing cyclopentadienyl–amide chelate ligands were synthesized and characterized by X‐ray analysis. The complexes function as effective proton‐coupled electron transfer (PCET) catalysts, facilitating molybdenum‐catalyzed ammonia formation from dinitrogen under ambient conditions.
Taichi Mitsumoto   +4 more
wiley   +1 more source

Tunable Endo/Exo Selectivity in Direct Catalytic Asymmetric 1,3‐Dipolar Cycloadditions with Polyfunctional Lewis Acid / Azolium‐Aryloxide Catalysts

open access: yesAngewandte Chemie International Edition, Accepted Article.
Catalytic asymmetric 1,3‐dipolar cycloadditions (1,3‐DCA) using iminoesters as ylide precursors offer a powerful approach to accessing stereochemically complex, biologically relevant pyrrolidines. While previous studies have already achieved impressive stereoselectivities, catalytic productivity remains a challenge, with turnover numbers (TON ...
Adrian Bürstner   +13 more
wiley   +1 more source

Trigonal Planar Bis(carbene)Cu(I) Complexes Enable Divergent H2 Activation with H2O for Accelerated Olefin Hydrogenation

open access: yesAngewandte Chemie International Edition, Accepted Article.
CuH‐catalyzed olefin hydrogenation is rare compared to those of carbonyl‐derived substrates. Olefin insertion into Cu‐H to form Cu‐alkyl is ubiquitous; however, subsequent H2 activation remains unknown to our knowledge. Herein, we investigated the transformations of β‐H elimination, H2 cleavage, and catalytic olefin hydrogenation in a series of linear ...
Evan Patrick   +6 more
wiley   +1 more source

Pharmaceutical Services: a field under consolidation [PDF]

open access: gold, 2017
Claudia Garcia Serpa Osorio‐de‐Castro   +2 more
openalex  

Sustained Interferon Signature Suppression With Anifrolumab in a Patient With STING‐Associated Vasculopathy with Onset in Infancy Refractory to JAK Inhibitor and Dazukibart Therapy

open access: yesArthritis &Rheumatology, EarlyView.
Objective The objective was to report the safety and efficacy of an anti‐IFNAR1 antibody (anifrolumab) in a patient with STING‐associated vasculopathy with onset in infancy (SAVI) who presented with vasculitic ulcers and systemic inflammation refractory to JAK inhibition (JAKi) and to the interferon‐β–neutralizing monoclonal antibody dazukibart ...
Sara Alehashemi   +13 more
wiley   +1 more source

Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler   +18 more
wiley   +1 more source

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