Results 31 to 40 of about 25,044 (295)
Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]
, 2008 In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
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Foresight Scanning: Future Directions of Clinical and Pharmaceutical Research
Journal of Pharmacy & Pharmaceutical Sciences, 2009 Foresight Scanning: Future Directions of Clinical and Pharmaceutical Research. Brian C. Foster, Therapeutic Products Directorate, Health Canada, Ottawa, Ontario, Canada ABSTRACT The Canadian Society for Pharmaceutical Sciences Satellite Symposium
Brian C. Foster
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The Application of Nanogels as Efficient Drug Delivery Platforms for Dermal/Transdermal Delivery
Gels, 2023 The delivery of active molecules via the skin seems to be an efficient technology, given the various disadvantages of oral drug administration. Skin, which is the largest human organ of the body, has the important role of acting as a barrier for ...
Panoraia I. Siafaka +4 more
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Does the Vehicle Matter? Real-World Evidence on Adherence to Topical Treatment in Psoriasis
Pharmaceutics, 2021 The influence of the vehicle in topical treatment adherence remains to be elucidated. The aim of this study is to analyze the influence of the pharmaceutical dosage form on adherence to topical treatment in psoriasis patients, taking into consideration ...
Ana Teixeira +8 more
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, 2021 [[abstract]]Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages of protecting against hepatic first-pass metabolism of the drug and improving its pharmacokinetic performance.
Miao, YB;Lin, YJ;Chen, KH;Luo, PK;Chuang, SH;Yu, YT;Tai, HM;Chen, CT;Lin, KJ;Sung, HW
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Oral pharmacokinetics of a pharmaceutical preparation of florfenicol in broiler chickens
Frontiers in Veterinary Science, 2023 IntroductionThe use of florfenicol must follow particular pharmacokinetic/pharmacodynamic (PK/PD) ratios, i.e., it requires achieving serum concentrations at or slightly above the pathogen's minimum inhibitory concentration (MIC) during the dosing ...
Lilia Gutierrez +4 more
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The effect of excipients on pharmacokinetic parameters of parenteral drugs [PDF]
, 2005 In the pharmaceutical industry, the main goal of early phase in vivo studies is to assess pharmacokinetic properties of a compound in laboratory animals. These data provide a basis for selecting and optimizing drug candidates.
Egger-Heigold, Barbara
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Membranes, 2021 In many instances, one or more components of a pharmaceutical or cosmetic formulation is an oil. The aims of this study were two-fold. First, to examine the potential of preferential uptake of one oily vehicle component over another into a model barrier ...
Omaima N. Najib +5 more
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Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma [PDF]
Pharmaceutical Sciences, 2022 In the pharmaceutical industry, liposomes and polymeric nanoparticles are the two most commonly studied delivery vehicles. A new technique uses lipid-polymeric hybrid nanoparticles (LPHNPs) with a polymeric core, and a shell made up of lipid-lipid-PEG ...
Yudhishtir Singh Baghel +1 more
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Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes
Pharmaceutics, 2021 The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug ...
Javiana Luengo +4 more
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