Results 131 to 140 of about 115,679 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The Role of Pharmacist in Medication Adherence:A Systematic Review
, 2019 Background: Medication adherence, which is how much is the patient committed to their medications, is an important factor in improving clinical outcomes and reducing mortalities. This adherence issue should not be the responsibility of the patients and
Aloulabi, Alaa
core
, 2020 Pharmacist-led intervention to improve medication use in older inpatients using the Drug Burden Index: A study protocol for a before/after intervention with a retrospective control group and multiple case ...
L Kouladjian O'Donnell (13404804) +12 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Think health, think pharmacist
As the roles of pharmacists continue to expand, there is an urgent need for strategic workforce planning to ensure we have enough professionals to meet Malaysia’s growing health care demands.
Long, Chiau Ming *
core
Pharmacist-provided quantitative heel ultrasound screening for rural women at risk of osteoporosis
, 2006 BACKGROUND: Osteoporosis is underdiagnosed, and rural communities often have limited technical resources for the assessment of osteoporosis. OBJECTIVE: To evaluate the impact of a pharmacist, trained in the use of a portable heel ultrasound device, in ...
Naunton, M (15504086) +2 more
core
Pharmacist-led medicines optimisation service in an inpatient mental health setting
Medicines optimisation ensures that people get the best possible outcomes from their medicines. As those with severe mental illness (SMI) are frequently prescribed psychotropic medicines with potentially significant side-effects, poor adherence to ...
Georgina Gilsenan (17815390) +7 more
core +1 more source
Assessment of Dofetilide or Sotalol Tolerability in the Elderly
Journal of Cardiovascular Pharmacology and TherapeuticsBackground: Dofetilide and sotalol are potassium channel antagonists that require inpatient QTc monitoring during initiation, due to increased risk of fatal arrhythmias.
Nikitha Yagnala PharmD +4 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source