Results 171 to 180 of about 115,679 (313)

Role of the pharmacist in reducing healthcare costs: current insights

, 2017
Kieran Dalton, Stephen Byrne Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork, Ireland Abstract: Global healthcare expenditure is escalating at an unsustainable rate.
Dalton K, Byrne S
core  

Clinical pharmacists' aspirations on prescribing in cardiology within an academic health system. [PDF]

Explor Res Clin Soc Pharm
Zachariah S, Nabil S, Thomas A, Castell S, Sayegh S, Thomas D.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Use of failure mode and effects analysis for risk analysis of investigational drug products management in clinical trials. [PDF]

Am J Health Syst Pharm
Zhang B, Song M, Wang Z, Zhou Y, Pang X.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Nephrotoxic medication burden and drug-related problems in patients with chronic kidney disease using SGLT2 inhibitors. [PDF]

Ren Fail
Ozturk Yalcin Z, Erdut A, Haberal G, Arici M, Bayraktar-Ekincioglu A.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Residents Preferences for Pharmacist-Managed Clinic in China: A Discrete Choice Experiment

Qingran Sun, Yi Wang, Pei Wang, Yuankai Huang, Xiaoyu Xi National Medical Products Administration Key Laboratory for Drug Regulatory Innovation and Evaluation, China Pharmaceutical University, Nanjing, Jiangsu Province, People’s Republic of ...
Xi X, Wang P, Huang Y, Sun Q, Wang Y
core  

Pharmacist interventions for obesity: improving treatment adherence and patient outcomes

, 2015
Melanie A Jordan, Jonathan HarmonCollege of Pharmacy – Glendale, Midwestern University, Glendale, AZ, USAAbstract: Obesity is currently a worldwide pandemic, with overweight (body mass index [BMI] ≥25 kg/m2) and obesity (BMI ≥30 kg/m2 ...
Harmon J, Jordan MA
core  

Development and validation of the 9-item Patient Satisfaction Questionnaire (PSQ-9) for use in community pharmacy settings. [PDF]

J Pharm Policy Pract
Sakr F, Dabbous M, Safwan J, El Bakri M, Rahal M, Salameh P.   +5 more
europepmc   +1 more source