Results 281 to 290 of about 347,518 (361)

Institutional Drug Information Dissemination in Ghana: Barriers, Enablers, and System-Level insights

Asare BA, Abassah-Konadu E, Amankwah I, Tabariyeng JN, Afriyie-Twumasi A, Adu M, Otoo DD, Yevutsey SK, Dalaba MA, Immurana M, Aberese-Ako M, Azeez J, Ansah E, Okorosobo T, Ogundahunsi O, Hodgson A, Gyapong M.   +16 more
europepmc   +1 more source

Antimicrobial stewardship resourcing and programme outcomes: a scoping review. [PDF]

JAC Antimicrob Resist
Langford BJ, Kang AY, Ji M, Bhatjire P, Huynh K, Lim S, McArthur A, Brown K, Daneman N, Schwartz KL, Leung V.   +10 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Combating Antimicrobial Resistance: A Pharmacist-Led PDCA Stewardship Program in a Tertiary Hospital. [PDF]

Infect Drug Resist
Li C, Han B, Lv L, Jiang H, Zhang M, Chen N, Xin C, Ying Y, Yang B.   +8 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Isavuconazole in Pediatric Invasive Fungal Infections: Outcomes and Therapeutic Drug Monitoring in a Chinese Multicenter Case Series. [PDF]

Infect Drug Resist
Zou S, Shu C, Liang X, Liu C, Luo P, Chen Z, Xu D, Liu D, Zhang J, He Y.   +9 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Individualizing beta-lactam dosing in real-world patients: lessons from a pharmacist-led programme implementation and evaluation. [PDF]

JAC Antimicrob Resist
Pan S, Weslander E, Fierek S, Ball M, Crutchfield CA, Galvin S, Rhodes NJ.   +6 more
europepmc   +1 more source

Optimising multidisciplinary team care in paediatric inflammatory bowel disease: a healthcare improvement initiative from a dedicated referral centre. [PDF]

BMJ Open Qual
Dipasquale V, DelNero N, Liddiard G, Hinchliffe C, Hubbard R, Londt Z, Narula P, Kapoor A.   +7 more
europepmc   +1 more source

Implementing Early Depression Screening as Routine Practice in Pharmacy Settings. [PDF]

J Patient Exp
Vutova Y, Slavchev G, Ignatova D, Kamusheva М.   +3 more
europepmc   +1 more source