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Pharmacoepidemiology and rheumatic disorders [PDF]

Rheumatic Disease Clinics of North America, 2004
This article reviews the application of pharmacoepidemiology in the evaluation of drugs that are used commonly for rheumatic disorders. Data sources and methodology considerations for these studies are highlighted. The topics that are covered included the safety evaluation of nonsteroidal ant-inflammatory drugs, adverse pregnancy outcomes of ...
Sonia Hernandez-Diaz, K. Arnold Chan
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Pharmacoepidemiological perspectives

Journal of Clinical Epidemiology, 1992
Parallel with increasing concerns about drug safety, the importance of drug surveillance and the application of epidemiologic techniques have grown rapidly during the past decades. The increasing use of computerized health care data facilitates the establishment of populations large enough (millions) to allow epidemiological studies.
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Pharmacoepidemiology in Pharmacogenetics

2018
Epidemiologic methods provide rigorous means by which to study the interplay between genetic factors and drug response. In this chapter, we describe the differences between experimental and observational study designs, and illustrate how to implement the highly efficient case-control study design.
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Base de Datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP): A data resource for pharmacoepidemiology in Spain

Pharmacoepidemiology and Drug Safety, 2020
Base de Datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP) is a population based database administered by the AEMPS (Spanish Agency for Medicines) of longitudinal electronic medical records (EMR) of patients attended in ...
Miguel-Ángel Maciá-Martínez, M. Gil, C. Huerta, E. Martín-Merino, A. Álvarez, V. Bryant, D. Montero   +6 more
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Analgesic Risks and Pharmacoepidemiology

JAMA: The Journal of the American Medical Association, 1986
Knowledge of uncommon adverse drug reactions ordinarily derives from case reports based on clinical observations. Size limitations of clinical trials preclude identification of rare adverse reactions.1Yet individual case reports have two problems. First, an observed clinical event may be coincidental to a particular drug exposure, be linked to the ...
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The intriguing future of pharmacoepidemiology

European Journal of Clinical Pharmacology, 2013
Over the years more and more data have become available in the constantly growing databases on prescription drugs. This has facilitated the development of pharmacoepidemiology, a dynamic research field that has undergone a more rapid development than many other research areas. There are several reasons why pharmacoepidemiology will remain recognized as
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Keeping the Pharmacology in Pharmacoepidemiology

Clinical Pharmacology & Therapeutics, 2020
The treatment of many medical conditions requires the use of multiple drugs. A study published recently in this journal nicely illustrates the need to consider the pharmacology of potentially interacting drugs when conducting pharmacoepidemiologic studies of patient safety outcomes associated with such interactions.
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Introduction To Pharmacoepidemiology

Annals of Pharmacotherapy, 1987
Abraham G. Hartzema, Hugh H. Tilson, Miquel Porta   +2 more
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An introduction to herbal pharmacoepidemiology

Journal of Ethnopharmacology, 1993
Herbal pharmacoepidemiology concerns itself with herbal drug uses and effects in large numbers of people. This new methodology can make substantial contributions to our understanding of herbal drug markets. Not only can it improve the timely detection and the quantitation of adverse reactions to botanical medicines, it can also help us to recognize ...
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Interpretation of Associations in Pharmacoepidemiology

Seminars in Hematology, 2008
Pharmacoepidemiology is an important tool for understanding and documenting the relationships between the use of drugs and adverse events. Side effects are an important consideration for clinicians making treatment decisions, and they also figure prominently in action by regulatory agencies.
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