Results 41 to 50 of about 36,199 (325)

Nine years of comparative effectiveness research education and training: initiative supported by the PhRMA Foundation [PDF]

open access: yes, 2018
The term comparative effectiveness research (CER) took center stage with passage of the American Recovery and Reinvestment Act (2009). The companion US$1.1 billion in funding prompted the launch of initiatives to train the scientific workforce capable of
Brixner, Diana I   +9 more
core   +1 more source

Patient Characteristics Associated with Repeat Antibiotic Prescribing Pre- and during the COVID-19 Pandemic: A Retrospective Nationwide Cohort Study of >19 Million Primary Care Records Using the OpenSAFELY Platform

open access: yesPharmacoepidemiology, 2023
COVID-19 pandemic-related pressures on primary care may have driven the inappropriate continuation of antibiotic prescriptions. Yet, prescribing modality (repeat/non-repeat) has not previously been investigated in a pandemic context. With the approval of
Alex Orlek   +7 more
doaj   +1 more source

What does validation of cases in electronic record databases mean? The potential contribution of free text [PDF]

open access: yes, 2011
Electronic health records are increasingly used for research. The definition of cases or endpoints often relies on the use of coded diagnostic data, using a pre-selected group of codes.
Cassell, Jackie A   +3 more
core   +3 more sources

Treatment-Related Late Adverse Events in Childhood Cancer Survivors of Mexico: A Cross-Sectional Study

open access: yesPharmacoepidemiology, 2023
Late adverse events (LAEs) are an important cause of illness and disability in childhood cancer survivors (CCSs) and increase the risk of mortality. The aim of this cross-sectional study was to describe the frequency and severity of treatment-related ...
José Fernando Pérez-Franco   +6 more
doaj   +1 more source

Core concepts in pharmacoepidemiology: Fundamentals of the cohort and case–control study designs

open access: yesPharmacoepidemiology and Drug Safety, 2022
In this review paper, I outline the principles of the cohort as a sampling frame and provide a basic introduction to the cohort study design and the case–control study design, two of the most important designs in the pharmacoepidemiologist's toolbox ...
A. Pottegård
semanticscholar   +1 more source

Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease? [PDF]

open access: yes, 2017
Pharmacoepidemiology studies are increasingly used for research into safe prescribing in chronic kidney disease (CKD). Typically, patients prescribed a drug are compared with patients who are not on the drug and outcomes are compared to draw conclusions ...
Douglas, Ian   +3 more
core   +1 more source

General Practitioner-Related Factors Associated with Antibiotic Prescription in Community-Dwelling Adult Population

open access: yesPharmacoepidemiology, 2023
Background: The extensive use of antibiotics has contributed to the development of antibiotic resistance. Understanding the factors behind the attitude of physicians in prescribing antibiotics may be useful to address educational interventions to ...
Sara Mandelli   +4 more
doaj   +1 more source

Pharmacovigilance and Pharmacoepidemiology as a Guarantee of Patient Safety: The Role of the Clinical Pharmacologist

open access: yesJournal of Clinical Medicine, 2022
Recent years, particularly the COVID-19 pandemic, can be considered a turning point for pharmacovigilance and pharmacoepidemiology in terms of their role in drug safety and drug utilisation monitoring in clinical practice [...].
G. Crescioli   +5 more
semanticscholar   +1 more source

Thromboembolic and neurologic sequelae of discontinuation of an antihyperlipidemic drug during ongoing warfarin therapy [PDF]

open access: yes, 2017
Warfarin and antihyperlipidemics are commonly co-prescribed. Some antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system.
Bilker, Warren B.   +5 more
core   +2 more sources

Feasibility of Using Oncology-Specific Electronic Health Record (EHR) Data to Emulate Clinical Trial Eligibility Criteria

open access: yesPharmacoepidemiology, 2023
We examined eligibility criteria from recent oncology clinical trials to see whether real-world data (RWD) from electronic health records (EHRs) could be used to create external control groups for clinical trials.
Thomas W. Wilson   +5 more
doaj   +1 more source

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