Results 41 to 50 of about 36,199 (325)
Nine years of comparative effectiveness research education and training: initiative supported by the PhRMA Foundation [PDF]
The term comparative effectiveness research (CER) took center stage with passage of the American Recovery and Reinvestment Act (2009). The companion US$1.1 billion in funding prompted the launch of initiatives to train the scientific workforce capable of
Brixner, Diana I+9 more
core +1 more source
COVID-19 pandemic-related pressures on primary care may have driven the inappropriate continuation of antibiotic prescriptions. Yet, prescribing modality (repeat/non-repeat) has not previously been investigated in a pandemic context. With the approval of
Alex Orlek+7 more
doaj +1 more source
What does validation of cases in electronic record databases mean? The potential contribution of free text [PDF]
Electronic health records are increasingly used for research. The definition of cases or endpoints often relies on the use of coded diagnostic data, using a pre-selected group of codes.
Cassell, Jackie A+3 more
core +3 more sources
Late adverse events (LAEs) are an important cause of illness and disability in childhood cancer survivors (CCSs) and increase the risk of mortality. The aim of this cross-sectional study was to describe the frequency and severity of treatment-related ...
José Fernando Pérez-Franco+6 more
doaj +1 more source
Core concepts in pharmacoepidemiology: Fundamentals of the cohort and case–control study designs
In this review paper, I outline the principles of the cohort as a sampling frame and provide a basic introduction to the cohort study design and the case–control study design, two of the most important designs in the pharmacoepidemiologist's toolbox ...
A. Pottegård
semanticscholar +1 more source
Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease? [PDF]
Pharmacoepidemiology studies are increasingly used for research into safe prescribing in chronic kidney disease (CKD). Typically, patients prescribed a drug are compared with patients who are not on the drug and outcomes are compared to draw conclusions ...
Douglas, Ian+3 more
core +1 more source
Background: The extensive use of antibiotics has contributed to the development of antibiotic resistance. Understanding the factors behind the attitude of physicians in prescribing antibiotics may be useful to address educational interventions to ...
Sara Mandelli+4 more
doaj +1 more source
Recent years, particularly the COVID-19 pandemic, can be considered a turning point for pharmacovigilance and pharmacoepidemiology in terms of their role in drug safety and drug utilisation monitoring in clinical practice [...].
G. Crescioli+5 more
semanticscholar +1 more source
Thromboembolic and neurologic sequelae of discontinuation of an antihyperlipidemic drug during ongoing warfarin therapy [PDF]
Warfarin and antihyperlipidemics are commonly co-prescribed. Some antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system.
Bilker, Warren B.+5 more
core +2 more sources
We examined eligibility criteria from recent oncology clinical trials to see whether real-world data (RWD) from electronic health records (EHRs) could be used to create external control groups for clinical trials.
Thomas W. Wilson+5 more
doaj +1 more source