Results 41 to 50 of about 34,898 (217)

Identifying Candidate Risk Factors for Prescription Drug Side Effects using Causal Contrast Set Mining [PDF]

, 2015
Big longitudinal observational databases present the opportunity to extract new knowledge in a cost effective manner. Unfortunately, the ability of these databases to be used for causal inference is limited due to the passive way in which the data are ...
Aickelin, Uwe, Guo, Zhaoyang, Reps, Jenna, Zhu, Haoyue   +3 more
core   +3 more sources

Patterns of risk of cancer in patients with metal-on-metal hip replacements versus other bearing surface types: a record linkage study between a prospective joint registry and general practice electronic health records in England. [PDF]

, 2013
BACKGROUND: There are concerns that metal-on-metal hip implants may cause cancer. The objective of this study was to evaluate patterns and timing of risk of cancer in patients with metal-on-metal total hip replacements (THR).
de Vries, Frank, Lalmohamed, Arief, Leufkens, Hubertus G M, MacGregor, Alexander J, Van Staa, Tjeerd, van Staa, Tjeerd P   +5 more
core   +5 more sources

Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink [PDF]

, 2015
Purpose: To investigate the association between the GABAergic drugs, benzodiazepines or zopiclone, and the occurrence of asthma exacerbations and subsequent mortality in a cohort of asthma patients. Methods: 105,747 patients without asthma exacerbation
Myles, Puja R., Nakafero, Georgina, Nguyen-Van-Tam, Jonathan S., Sanders, Robert D.   +3 more
core   +4 more sources

Interactive exploration of population scale pharmacoepidemiology datasets

, 2020
Population-scale drug prescription data linked with adverse drug reaction (ADR) data supports the fitting of models large enough to detect drug use and ADR patterns that are not detectable using traditional methods on smaller datasets. However, detecting
Abadi M., Furu K., Salathé M., Ventola C. L., Wishart D. S.   +4 more
core   +1 more source

Nine years of comparative effectiveness research education and training: initiative supported by the PhRMA Foundation [PDF]

, 2018
The term comparative effectiveness research (CER) took center stage with passage of the American Recovery and Reinvestment Act (2009). The companion US$1.1 billion in funding prompted the launch of initiatives to train the scientific workforce capable of
Brixner, Diana I, Cannon, Eileen, Devine, Emily Beth, Gagnon, Jean Paul, Garrison, Louis P, Murray, Michael D, Perfetto, Eleanor, Pickard, A Simon, Schumock, Glen T, Segal, Jodi B   +9 more
core   +1 more source

Self-efficacy and medicine use for headache among adolescents in Italy: results from the Italian HBSC 2010 study [PDF]

, 2015
This article aims first to investigate gender patterns in medicine use, and corresponding headache complaints, in Italian adolescents; second, to examine the association between self-efficacy and medicine use for headache.
Cavallo, Franco, Marino, Claudia, Santinello, Massimo, Vieno, Alessio   +3 more
core   +1 more source

Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort [PDF]

, 2016
BACKGROUND: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings.
Abbas, Zaigham, Abdou, Ahmed Mohamed Saleh, Abou Rached, Antoine, Acalovschi, Monica, Afredj, Nawel, Ahlers, Silke, Ahmetagic, Sead, Ahn, Sang Hoon, Aissaoui, Magda, Akriviades, Euaggelos, Al Ghandoor, Zuhal, Al Gharabally, Abeer, Al Qameesh, Jihad, Alavian, Seyed Moayed, Alberto, Sara, Aleixo, Maria Jo\ue3o, Amedea, Alessandri, Amoroso, Pietro, Ancuta, Ioan, Andreica, Vasile, Andreoni, Massimo, Arama, Victoria, Ascione, Antonio, Askar, Haifa, Assene, Collins, Attili, Adolfo Francesco, Augustyniak, Krystyna, Baka Cwierz, Barbara, Bakalos, Georgios, Bandiera, Franco, Banyai, Tivadar, Basho, Jovan, Bassi, Paolo, Bastens, Boris, Bellantani, Stefano, Bellati, Giorgio, Berak, Hanna, Bevanda, Milenko, Bhalla, Ajay, Biglino, Alberto, Bocakova, Jana, Bourgeois, Stefan, Brixko, Christian, Brunetto, Maurizia, Bruno, Savino, Bunganic, Ivan, Calkic, Lejla, Caruntu, Florin, Casinelli, Katia, Castellacci, Roberto, Castelli, Francesco, Cattelan, Anna Maria, Chiriaco, Piergiorgio, Cijevschi, Cristina, Colletta, Cosimo, Colombo, Massimo, Colombo, Silvia, Coman, Felicia, Cool, Mike, Coppola, Carmine, Correa, Maria Cassia, Costa, Chiara, Craxi, Antonio, Curescu, Manuela, D'Amico, Emilio, D'Angelo, Salvatore, Daryani, Nasser Ebrahimi, De Galocsy, Chantal, Debzi, Nabil, Decaestecker, Jochen, Delic, Dragan, Delwaide, Jean, Demelia, Luigi, Derbala, Moutaz, Deron, Zbigniew, Di Giacomo, Antonio, Di Perri, Giovanni, Dimitroulopoulos, Dimitrios, Dohaibi, Ahmad, Drakoulis, Christos, Drenaggi, Davide, Elefsiniotis, Ioannis, Enyedi, Judit, Erne, Elke, Esmat, Gamal, Evgenidis, Nikolaos, Fabri, Milotka, Faria, Telo, Ferenci, Peter, Fernandes, Julio Cesar, Ferrari, Carlo, Ferraz, Maria Lucia, Fierbinteanu Braticevici, Carmen, Flisiak, Robert, Foster, Graham R., Foti, Giuseppe, Francisci, Daniela, Fried, Katalin, Gabr, Mamdouh, Ganga, Roberto, George, Christophe, Gervain, Judit, Gheorghe, Liana, Giannoulis, Grigoris, Gietka, Andrzej, Giguere, Alain, Gomide, Geisa, Guerreiro, Hor\ue1cio, Guessab, Nawal, Halota, Waldemar, Han, Sang Young, Hanno, Abdelfatah, Harxhi, Arjan, Hashmi, Zahid, Hassanein, Tarek, Hausinger, P\ue9ter, Henrion, Jean, Holoman, Jozef, Horsmans, Yves, Hoste, Paul, Houmani, Zaher, Hunyady, Bela, Ibrahimpasic, Nevzeta, Ionita Radu, Florentina, Ivanovski, Ljubomir, Jablkowski, Maciej, Jankovic, Goran, Janssens, Filip, Jarcuska, Peter, Jesic, Rada, Joksimovic, Nenad, Junior, Elson Martins, Juriens, Ir\ue8ne, Kanatakis, Stilianos, Karagiannis, Ioannis, Karatapanis, Stilianos, Ketikoglou, Ioannis, Kim, Yoonjun, Konstantinovic, Ljiljana, Krkoska, Dusan, Kupcova, Viera, Lakner, Lilla, Langlet, Philippe, Lasser, Luc, Laukens, Pierre, Lawate, Parimal, Lee, Yun Nah, Lefebvre, Veronique, Lencu, Monica, Lengyel, Gabriella, Lesch, Miklos, Lipczynski, Artur, Livia, Hara, Luaia, Rosang, Lyra, Andre, Macedo, Guilherme, Mahindad, Nadir, Mahiou, Hassene, Makkai, Erzs\ue9bet, Malhado, Jos\ue9, Manesis, Emmanuel, Mangia, Alessandra, Manolakopoulos, Spilios, Mansinho, Kamal, Martinet, Jean Paul, Masood, Siddiq, Matarazzo, Filippo, Mazur, Wlodzimierz, Mazzella, Giuseppe, Mazzeo, Maurizio, Megna, Angelo Salomone, Mela, Maria, Mello, Carlos Eduardo, Memoli, Massimo, Memon, Sadik, Mendes, Claudio, Merat, Shahin, Mesihovic, Rusmir, Michielsen, Peter, Miftode, Egidia, Mimidis, Konstantinos, Mohsin, Aftab, Montalbano, Marzia, Montalto, Giuseppe, Monteverde, Carlos, Motoc, Adriana, Mousoulis, Georgios, Mulkay, Jean Pierre, Musat, Marioara, Musialik, Joanna, Nagorni, Aleksandar, Nagral, Aabha, Nagy, Istvan, Nassiri Toosi, Mohsen, Nemes\ue1nszky, Elem\ue9r, Nevens, Frederik, Nikolopoulou, Vassiliki, Nozic, Darko, Olszok, Iwona, Olteanu, Dan, Oltman, Marian, Omar, Ashraf, Orfanou, Eleni, Orlandini, Alessandra, Orszulak, Grazyna, Ozsv\ue1r, Zs\uf3fia, Paik, Seung Woon, Parikh, Samir, Pascu, Oliviu, Passariello, Nicola, Patai, \uc1rp\ue1d, Peixe, Paula, Pelemis, Mijomir, Pereira, Patricia, Philip, Mathew, Picciotto, Antonio, Piekarska, Anna, Piekos, Tomasz, Pieri, Alessandro, Pietrangelo, Antonello, Pigozzi, Maria Graziella, Pirisi, Mario, Preotescu, Liliana, Quirino, Tiziana, Racz, Istvan, Radowska, Danuta, Raimondo, Giovanni, Ramos, Jos\ue9 Presa, Rao, Padaki, Rapaccini, Gian Ludovico, Reddy, K. Rajender, Reynaert, Hendrik, Ribiczey, P\ue1l, Rizzardini, Giuliano, Rizzetto, Mario, Robaeys, Geert, Roxo, Fausto, Ruiz, Fernando Jose, Russello, Maurizio, Russo, FRANCESCO PAOLO, Sabusco, Giuseppe, Santantonio, Teresa, Saracco, Giorgio Maria, Sarmento Castro, Rui, Schneider, Ferenc, Schreter, Ivan, Schuller, J\ue1nos, Serejo, F\ue1tima, Servais, Benoit, Shabanaj, Gentian, Sharara, Ala, Shiffman, Mitchell L., Sieklucki, Jerzy, Silaghi, Rodica, Silva, Giovanni, Silva, Mariliza Henrique, Simon, Krzysztof, Skladany, Lubomir, Soardo, Giorgio, Somani, Sanjay, Sood, Ajit, Spinzi, Giancarlo, Sporea, Ioan, Sprengers, Dirk, Stan, Marioara, Stanciu, Carol, Streinu Cercel, Adrian, Svorcan, Petar, Szalay, Ferenc, Szantova, Maria, Szentgy\uf6rgyi, L\ue1szl\uf3, Szlauer, Bronislawa, Tallarico, Ludovico, Teixeira, Rosangela, Todorovic, Zoran, Tolvaj, Gyula, Tornai, Istvan, Trifan, Anca, Tsianos, Epameinondas, Tundo, Paolo, Tusnadi, Anna, V\ue1czi, Zsuzsanna, Vafiadi Zoubouli, Irini, Valente, Cristina, Van Der Meersch, Filip, Van Vlierberghe, Hans, Varga, Marta, Varghese, Rosh, Varkonyi, Istvan, Velez, Jorge, Verhaz, Antonija, Verucchi, Gabriella, Vinci, Maria, Vincze, Aron, Vinelli, Francesco, Warakomska, Iwona, Warzee, Philippe, Yaghi, Cesar, Yang, Jinmo, Yousry, Ayman, Zaarour, Fouad, Zali, Mohammad Reza, Zignego, Anna Linda, Zuin, Massimo   +303 more
core   +1 more source

Bayesian model selection in logistic regression for the detection of adverse drug reactions [PDF]

, 2015
Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods.
Marbac, Matthieu, Sedki, Mohammed, Tubert-Bitter, Pascale   +2 more
core   +2 more sources

Imported malaria in the UK, 2005 to 2016: estimates from primary care electronic health records [PDF]

, 2018
Objective To investigate trends in the incidence of imported malaria in the UK between 2005 and 2016. Design Analysis of longitudinal electronic health records (EHRs) in The Health Improvement Network (THIN) primary care database.
Bastaki, Hamad, Cassell, Jackie, Marston, Louise, Rait, Greta   +3 more
core   +3 more sources

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source