Results 41 to 50 of about 25,921 (246)

Pharmacoepidemiology day 2023: a fun and interactive way to understand pharmacoepidemiology / Zakiah Mohd Noordin and Dr. Mahmathi Karuppannan [PDF]

, 2023
Pharmacoepidemiology and Public Health course is offered to second year pharmacy students in their 2nd semester. The course introduces students to different types of pharmacoepidemiology study designs.
Karuppannan, Mahmathi, Mohd Noordin, Zakiah   +1 more
core  

Prescribing Patterns of Antibiotics According to the WHO AWaRe Classification during the COVID-19 Pandemic at a Teaching Hospital in Lusaka, Zambia: Implications for Strengthening of Antimicrobial Stewardship Programmes

Pharmacoepidemiology, 2023
Irrational and inappropriate prescribing of antibiotics is a major problem that can lead to the development of antimicrobial resistance (AMR). In Zambia, there is insufficient information on the prescribing patterns of antibiotics according to the World ...
Steward Mudenda, Eustus Nsofu, Patience Chisha, Victor Daka, Billy Chabalenge, Webrod Mufwambi, Henson Kainga, Manal H.G. Kanaan, Ruth L. Mfune, Florence Mwaba, Mildred Zulu, Rabecca Tembo, Wizaso Mwasinga, Kennedy Chishimba, Grace Mwikuma, Ngula Monde, Mulemba Samutela, Harriet K. Chiyangi, Shafiq Mohamed, Scott K. Matafwali   +19 more
doaj   +1 more source

Knowledge and Practices among Dental Practitioners Regarding the Use of Antimicrobials for Periodontal Diseases: An Online Survey in Saudi Arabia

Pharmacoepidemiology, 2023
This study aimed to investigate the knowledge and practices among dental practitioners in Saudi Arabia regarding the use of antimicrobials for periodontal diseases.
Mohammed Sultan Al-Ak’hali, Esam Halboub, Mona Awad Kamil, Wafa Hassan Alaajam, Abdulaziz Mahnashi, Jabbar Khubrani, Abdullah Mahnashi, Khalid Mahnashi, Nuha Farea   +8 more
doaj   +1 more source

Effects of Electronic Cigarette Use on Cardiovascular-Disease-Related Inflammatory Biomarkers in Smokers with HIV in a Switching Study in the United States

Pharmacoepidemiology, 2023
People with HIV (PWH) experience higher rates of cardiovascular events (CVEs) compared with the general population. A substantial body of evidence supports that select biomarkers of inflammation (soluble CD14 [sCD14], soluble CD163 [sCD163], highly ...
Patricia A. Cioe, William V. Lechner, Jennifer W. Tidey, Christopher W. Kahler   +3 more
doaj   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

British Journal of Clinical Pharmacology, EarlyView.
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann, Julian Peter Müller, Stefan Düsterhöft, Sabrina Yamoune, Katja Susanne Just, Julia Carolin Stingl   +5 more
wiley   +1 more source

Pharmacoepidemiological approaches for population-based hypothesis testing [PDF]

, 2018
Pharmacoepidemiology aims to study the use and both the adverse and beneficial effects of drugs and vaccines in the population after market authorization. The efficacy of drugs is assessed in experimental studies before a drug is allowed on the market in
Klungel, Olaf H., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Olaf H. Klungel   +3 more
core   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Improving Propensity Score Methods in Pharmacoepidemiology

, 2014
Inferences about intended effects of treatments are ideally investigated using randomized control trials (RCTs). Randomization leads to comparability of treated and comparison groups on measured and unmeasured prognostic factors, except the treatment ...
Pharmacoepidemiology, Sub Pharmacotherapy, Theoretical, Ali, M.S., Pharmacoepidemiology and Clinical Pharmacology   +3 more
core   +1 more source