Results 31 to 40 of about 744,413 (213)

Phytochemistry, Pharmacology, and Nutraceutical Profile of Carissa Species: An Updated Review

Molecules, 2021
Carissa, a genus of the Apocynaceae family, consists of evergreen species, such as shrubs as well as small trees that are native to Asia, Africa, and Oceania’s subtropical and tropical regions.
Jyoti Dhatwalia, Amita Kumari, Rachna Verma, Navneet Upadhyay, Ishita Guleria, Sohan Lal, Shabnam Thakur, Kasahun Gudeta, Vikas Kumar, Jane C.-J. Chao, Somesh Sharma, Ashwani Kumar, Amanda-Lee Ezra Manicum, José M. Lorenzo, Ryszard Amarowicz   +14 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

In Vitro Propagation, Phytochemical and Neuropharmacological Profiles of Bacopa monnieri (L.) Wettst.: A Review

Plants, 2020
Bacopa monnieri has been used as a reputed drug in the Indian traditional ayurvedic system for centuries. This medicinal herb with important phytopharmaceuticals has been popularly known as “Brahmi”. In recent years, B.
Partha Sarathi Saha, Sayantika Sarkar, Rajendran Jeyasri, Pandiyan Muthuramalingam, Manikandan Ramesh, Sumita Jha   +5 more
doaj   +1 more source

A Review of Rhazya stricta Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses

Plants, 2021
The local medicinal plant Rhazya stricta Decne is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features. R. stricta has been used widely in different cultures for various medical disorders.
Abdulaziz Albeshri, Nabih A. Baeshen, Thamer A. Bouback, Abdullah A. Aljaddawi   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

A Histopathological, Immunohistochemical and Biochemical Investigation on the in vitro Antioxidant, Myeloprotective, Hematoprotective and Hepatoprotective Effects of Hypericum triquetrifolium Seed Extract Against Cyclophosphamide-Induced Toxicity

Brazilian Archives of Biology and Technology
The aim of this study was to investigate in vitro antioxidant properties and in vivo protective effects of the methanol extract of the Hypericum triquetrifolium Turra (HT) seed against acute hepatotoxicity, myelotoxicity and hematotoxicity in rats ...
Songul Cetik Yildiz, Cumali Keskin, Varol Sahintürk, Adnan Ayhanci   +3 more
doaj   +1 more source

Synthesis and Reactivity of 3H-1,2-dithiole-3-thiones

Molecules, 2021
3H-1,2-Dithiole-3-thiones are among the best studied classes of polysulfur-containing heterocycles due to the almost explosive recent interest in these compounds as sources of hydrogen sulfide as an endogenously produced gaseous signaling molecule.
Oleg A. Rakitin
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Naturally Occurring Cinnamic Acid Sugar Ester Derivatives

Molecules, 2016
Cinnamic acid sugar ester derivatives (CASEDs) are a class of natural product with one or several phenylacrylic moieties linked with the non-anomeric carbon of a glycosyl skeleton part through ester bonds.
Yuxin Tian, Weirui Liu, Yi Lu, Yan Wang, Xiaoyi Chen, Shaojuan Bai, Yicheng Zhao, Ting He, Fengxue Lao, Yinghui Shang, Yu Guo, Gaimei She   +11 more
doaj   +1 more source

Development and Application of Indolines in Pharmaceuticals

ChemistryOpen, 2023
In recent years, the incidence of cancer is high around the world, and the resistance of bacteria is increasing. To cope with the potentially adverse side effects of cancer chemotherapy and surgery, researchers are turning to the construction of new drug
Huixin Wei, Bo Li, Ning Wang, Yitian Ma, Jingyan Yu, Xuena Wang, Jiayi Su, Prof. Dr. Dan Liu   +7 more
doaj   +1 more source