Results 261 to 270 of about 858,870 (284)
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Clinical pharmacology and malaria
Annals of Tropical Medicine And Parasitology, 1997The role of clinical pharmacology in improving the prevention and treatment of malaria is reviewed. A series of general and specific issues is discussed, concentrating on risk-benefit and cost-effectiveness. The techniques of clinical pharmacokinetics play an important role in the optimal use of drugs and this is illustrated by studies on quinine and ...
Alasdair Breckenridge, P. A. Winstanley
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Clinical Pharmacology Of Caffeine
Annual Review of Medicine, 1990Caffeine is the most widely consumed stimulant drug in the world. This chapter reviews the human pharmacology of caffeine; the evidence for its role in causing human disease, including addiction; and its potential usefulness as a therapeutic agent.
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CLINICAL PHARMACOLOGY OF BENZODIAZEPINES
Annual Review of Medicine, 1987The benzodiazepines are the most widely used anxiolytic drugs. Their pharmacokinetic properties differ widely. Side effects are usually mild but dependence can supervene after long-term administration, even if normal therapeutic doses are not exceeded. Careful monitoring of use is essential.
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Clinical Pharmacology of Nicotine
Annual Review of Medicine, 1986Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
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The clinical pharmacology of vasoconstrictors
Clinical Pharmacology & Therapeutics, 1966Vasoconstrictors are mainly used in acute hypotensive states, and they often succeed in bringing about at least a temporary increase in arterial pressure. Pressure is easy to measure, whereas tissue perfusion is not; but it is the latter that is the important variable, and a rise in pressure does not necessarily imply an improved circulation.
A. C. Dornhorst, R. L. Hodge
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Clinical pharmacology – the basics
Surgery (Oxford), 2009Abstract Clinical pharmacology is the study of pharmacodynamics and pharmacokinetics in humans. The relationship between dose, concentration and pharmacodynamic response may be explored using biomarkers for both desired and undesired effects of drugs.
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The chemistry, pharmacology and clinical pharmacology of diflunisal
Current Medical Research and Opinion, 1978Studies are reviewed on diflunisal, a new analgesic agent with an improved therapeutic index, compared with acetylsalicylic acid, in animals and humans. Pharmacokinetic data indicate that a twice-daily dosage regimen of diflunisal is adequate for therapeutic purposes.
V. J. Cirillo +2 more
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Clinical pharmacology in Australia
Clinical Pharmacology & Therapeutics, 1974In Australia, clinical pharmacology is a small but developing discipline useful for the generation of data concerning the efficacy and safety of new therapeutic substances. While most clinical pharmacology is carried on as an adiunct to the interests of a specialist in some branch of internal medicine, there are now, in Australia, four units titled ...
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Clinical Pharmacology of HFA134a
Journal of Aerosol Medicine, 1995The safety, tolerability and pharmacokinetics of the chlorine-free propellant HFA134a were assessed in healthy subjects after single and repeat doses. Absorption and disposition were investigated in healthy subjects and severe chronic obstructive pulmonary disease (COPD) patients using labelled HFA134a.
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