Molecules, 2022 Background: Nowadays, in Nuclear Medicine, clinically applied radiopharmaceuticals must meet quality release criteria such as high radiochemical purity and radiochemical yield.
Silvia Migliari +4 more
doaj +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]
, 2006 A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Bataille, Bernard +5 more
core +2 more sources
Modernization of Enoxaparin Molecular Weight Determination Using Homogeneous Standards
Pharmaceuticals, 2017 Enoxaparin is a low-molecular weight heparin used to treat thrombotic disorders. Following the fatal contamination of the heparin supply chain in 2007–2008, the U.S. Pharmacopeia (USP) and U.S.
Katelyn M. Arnold +7 more
doaj +1 more source
An in vitro aerosolization efficiency comparison of generic and branded salbutamol metered dose inhalers [PDF]
, 2017 Background: Due to the high rate of pulmonary diseases, respiratory drug delivery systems have been attracted excessive attention for the past decades.
Ghanbarzadeh, Saeed +3 more
core +2 more sources
USP compendial methods for analysis of heparin: chromatographic determination of molecular weight distributions for heparin sodium [PDF]
, 2016 Heparin is a polysaccharide product isolated from glycosaminoglycans of porcine mucosa (or occasionally other tissues and species). It is a linear non-uniform polymer consisting of alternating glucosamine and uronic acid monosaccharide residues and is ...
Al Hakim, Ali +6 more
core +1 more source
Проблемы особо опасных инфекций, 2018 Objective of the study was to analyze the basic quality parameters of the produced live plague vaccine and stability of the preparation during the storage process. Materials and methods.
A. A. Zuenko +7 more
doaj +1 more source
Assessment of efficacy and quality of two albendazole brands commonly used against soil-transmitted helminth infections in school children in Jimma Town, Ethiopia [PDF]
, 2015 Background : There is a worldwide upscale in mass drug administration (MDA) programs to control the morbidity caused by soil-transmitted helminths (STHs): Ascaris lumbricoides, Trichuris trichiura and hookworm. Although anthelminthic drugs which are used
D'Hondt, Matthias +11 more
core +4 more sources
Comparative Analysis of Compendial Quality Requirements for Carvedilol Products
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. Carvedilol is a drug used to treat renovascular hypertension and cardiovascular diseases. A monograph for carvedilol drug substance has been included in the State Pharmacopeia of the Russian Federation (SP RF); however, quality requirements
A. I. Belanova +2 more
doaj +1 more source
Journal of Pharmaceutical Analysis, 2018 Sulconazole has been reported to degrade into sulconazole sulfoxide via sulfur oxidation; however, structural characterization data was lacking and the potential formation of an N-oxide or sulfone could not be excluded.
Qun Xu +6 more
doaj +1 more source