USP compendial methods for analysis of heparin: chromatographic determination of molecular weight distributions for heparin sodium [PDF]
, 2016 Heparin is a polysaccharide product isolated from glycosaminoglycans of porcine mucosa (or occasionally other tissues and species). It is a linear non-uniform polymer consisting of alternating glucosamine and uronic acid monosaccharide residues and is ...
Al Hakim, Ali +6 more
core +1 more source
The Osmium Isotope Signature of Phanerozoic Large Igneous Provinces
Geophysical Monograph Series, Page 229-246., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Alexander J. Dickson +2 more
wiley +2 more sources
HPLC method validation for modernization of the tetracycline hydrochloride capsule USP monograph
Bulletin of Faculty of Pharmacy Cairo University, 2014 This paper is a continuation to our previous work aiming at development and validation of a reversed-phase HPLC for modernization of tetracycline-related USP monographs and the USP general chapter . Previous results showed that the method is accurate and
Emad M. Hussien
doaj +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Molecules, 2022 Background: Nowadays, in Nuclear Medicine, clinically applied radiopharmaceuticals must meet quality release criteria such as high radiochemical purity and radiochemical yield.
Silvia Migliari +4 more
doaj +1 more source
Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]
, 2006 A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Bataille, Bernard +5 more
core +2 more sources
Modernization of Enoxaparin Molecular Weight Determination Using Homogeneous Standards
Pharmaceuticals, 2017 Enoxaparin is a low-molecular weight heparin used to treat thrombotic disorders. Following the fatal contamination of the heparin supply chain in 2007–2008, the U.S. Pharmacopeia (USP) and U.S.
Katelyn M. Arnold +7 more
doaj +1 more source
The effect of spacer morphology on the aerosolization performance of metered-dose inhalers [PDF]
, 2016 Purpose: Respiratory drug delivery has been attracted great interest for the past decades, because of the high incidence of pulmonary diseases. However, despite its invaluable benefits, there are some major drawbacks in respiratory drug delivery, mainly ...
Barnes AR +4 more
core +2 more sources
A Pilot Chemical and Physical Stability Study of Extemporaneously Compounded Levetiracetam Intravenous Solution [PDF]
, 2015 Levetiracetam is a commonly used antiepileptic medication for tumor-related epilepsy. However, the 100 mL intravenous (IV) infusion volume can be burdensome to imminently dying hospice patients.
Hughes, Susan E. +3 more
core +2 more sources
Journal of Pharmaceutical Analysis, 2018 Sulconazole has been reported to degrade into sulconazole sulfoxide via sulfur oxidation; however, structural characterization data was lacking and the potential formation of an N-oxide or sulfone could not be excluded.
Qun Xu +6 more
doaj +1 more source