Results 141 to 150 of about 25,555 (231)

Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
Mast cells drive early allergic asthma by releasing histamine, interleukins and prostaglandins, causing airway hyperresponsiveness, mucus overproduction and inflammation. These events sustain symptoms and promote structural remodelling, contributing to the progression of the disease.
Iêda Maria dos Santos, João Lázaro de Oliveira Rocha, Edilson Beserra de Alencar Filho, Fabrício Souza Silva   +3 more
wiley   +1 more source

Molecular modeling to simulation: insights into Gaussian QSAR, molecular docking, and DFT for identification of HDAC3 inhibitors for neurocognitive vascular dementia. [PDF]

Sci Rep
Halder D, Banerjee S, Biswas S, Adhikari N, Ghosh B.   +4 more
europepmc   +1 more source

Identification of a novel and high-affinity cyclic peptide targeting Keap1 for inflammation treatment by a combined virtual screening strategy. [PDF]

J Enzyme Inhib Med Chem
Gao S, Shi X, Yang S, Wang Y, Wang Q, Yang M.   +5 more
europepmc   +1 more source

Explore Pharmacophore Diversity... [PDF]

Chemical & Engineering News Archive, 1995
openaire   +1 more source

Integrative molecular simulations reveal NeuroAid II mechanisms in ischemic stroke through network pharmacology, molecular dynamics, and pharmacophore modeling. [PDF]

Sci Rep
Dermawan D, Simatupang ST, Nadia N, Tan S, Tjandrawinata RR.   +4 more
europepmc   +1 more source

<i>De Novo</i> Drug Design, Synthesis, Biological Evaluation, and Structural Examination of Novel Coumarin-Based Pyrimidine Co-Drugs Accompanied by Molecular Docking and DFT Studies. [PDF]

ACS Omega
Naz N, Nazli ZI, Parveen S, Shafiq N.
europepmc   +1 more source

Exploration of Natural Products for Targeting IDH1/2 Mutations in Acute Myeloid Leukemia Through Ligand-Based Pharmacophore Screening, Docking, ADME-T, and Molecular Dynamic Simulation Approaches. [PDF]

Bioinform Biol Insights
Das U, Regati DR, Kumar J, Sowdhamini R.
europepmc   +1 more source

A Nonviral Neo-Nucleocapsid for Cell-Specific RNA Delivery Developed by Pseudo-Cyclic Peptide Grafting and Directed Evolution. [PDF]

Angew Chem Int Ed Engl
Kanayama D, Terasaka N, Kato K, Okazaki S, Suga H.   +4 more
europepmc   +1 more source

HyperPhS: a pharmacophore-guided multimodal representation framework for metabolic stability prediction through contrastive hypergraph learning. [PDF]

Bioinformatics
Liu X, Zhang N, Kang C, Ai C, Yang H, Tang J, Guo F.   +6 more
europepmc   +1 more source

In Silico Optimization of Inhibitors of the 3-Chymotrypsin-like Protease of SARS-CoV-2. [PDF]

Life (Basel)
Fofana I, Dali B, Koné M, Sujova K, Megnassan E, Miertus S, Frecer V.   +6 more
europepmc   +1 more source