Results 151 to 160 of about 36,254 (282)

Pharmacophore and docking-based virtual screening approach for the design of new dual inhibitors of Janus kinase 1 and Janus kinase 2

, 2014
Haneesh Jasuja, Navriti Chadha, Manminder Kaur, Om Silakari   +3 more
openalex   +2 more sources

Regulation of 11β-hydroxysteroid dehydrogenase isoforms: pharmacophore search and molecular design of prospective 11β-HSD1 inhibitors Authors

Research Results in Pharmacology
Introduction: Osteoporosis is an important medical and social public health problem in an aging or elderly society, the issue of pharmacological correction of which remains unresolved to this day.
Mikhail V. Korokin, Svetlana K. Kotovskaya, Tatyana V. Avtina, Ivan S. Koklin, Ilya I. Butorin, Konstantin V. Savateev, Grigoriy V. Urakov, Eduard I. Taran, Sergey V. Androv, Alim A. Kochkarov, Liliya V. Korokina, Victor V. Fedotov, Timofey D. Moseev, Oleg S. Gudyrev, Natalia V. Koroleva, Viktor V. Vasyutkin, Polina I. Pykhtina   +16 more
doaj   +1 more source

Exploring Novel ALK Inhibitors Using Energy Based Pharmacophore Mapping and High Throughput Virtual Screening [PDF]

, 2018
Nivya James, Raunaq Surana, Isha Thigale, Preethi B. Preethi, Shanthi V. Shanthi, K. Ramanathan   +5 more
openalex   +1 more source

On the Value of Homology Models for Virtual Screening: Discovering hCXCR3 Antagonists by Pharmacophore-Based and Structure-Based Approaches

, 2012
Dane Huang, Qiong Gu, Ge Hu, Ji‐Ming Ye, Noeris K. Salam, Arnie Hagler, Hongzhuan Chen, Jun Xu   +7 more
openalex   +1 more source

Pharmacophore based virtual screening of cholinesterase inhibitors: search of new potential drug candidates as antialzheimer agents. [PDF]

In Silico Pharmacol, 2022
Lakra N, Matore BW, Banjare P, Singh R, Singh J, Roy PP.   +5 more
europepmc   +1 more source

Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Discovery of Novel Akt2 Inhibitors

International Journal of Medical Sciences, 2013
Akt2 is considered as a potential target for cancer therapy. In order to find novel Akt2 inhibitors which have different scaffolds, structure-based pharmacophore model and 3D-QSAR pharmacophore model were built and validated by different methods.
Jia Fei, Lu Zhou, Tao Liu, Xiang-Yang Tang
doaj  

Brazilin from Caesalpinia sappan L. as a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor: Pharmacophore-Based Virtual Screening, In Silico Molecular Docking, and In Vitro Studies. [PDF]

Adv Pharmacol Pharm Sci, 2023
Iqbal M, Hasanah N, Arianto AD, Aryati WD, Puteri MU, Saputri FC.   +5 more
europepmc   +1 more source

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening

, 2015
Fanwang Meng, Su-Fang Cheng, Hong Ding, Shien Liu, Yan Liu, Kongkai Zhu, Shijie Chen, Junyan Lu, Yiqian Xie, Linjuan Li, Rongfeng Liu, Zhe Shi, Yu Zhou, Yu‐Chih Liu, Mingyue Zheng, Hualiang Jiang, Wencong Lu, Hong Liu, Cheng Luo   +18 more
openalex   +1 more source

Targeting the NF-κB/IκBα complex via fragment-based E-Pharmacophore virtual screening and binary QSAR models

, 2018
Tarek Kanan, Duaa Kanan, İsmail Erol, Samira Yazdi, Matthias Stein, Serdar Durdağı   +5 more
openalex   +2 more sources

Pharmacophore-based virtual screening and molecular docking simulation of terpenoid compounds as the inhibitor of sonic hedgehog protein for colorectal cancer therapy [PDF]

, 2019
Mega Maulina Ekawati, Mochammad Arfin Fardiansyah Nasution, Syafrida Siregar, Ilmi Fadhilah Rizki, Usman Sumo Friend Tambunan   +4 more
openalex   +1 more source