Results 11 to 20 of about 5,445 (212)

Analytical Quality by Design-Guided Optimisation and Validation of a Short-Run Stability-Indicating Reverse-Phase Ultra-Fast Liquid Chromatography (RP-UFLC) Method for the Quantitation of Nonivamide. [PDF]

Biomed Chromatogr
ABSTRACT Nonivamide (NON), a capsaicin analogue with similar pharmacological effects, is used in pain management, yet limited information exists on its accurate quantification by reverse‐phase liquid chromatography. A cost‐effective, efficient and precise RP‐HPLC method was developed, optimised using response surface methodology (central composite ...
Mahlangu P, Poka MS, Makoni PA, Witika BA.   +3 more
europepmc   +2 more sources

Comparative Analysis of Quality Requirements for Medicines Based on Horse-Chestnut Seeds

Регуляторные исследования и экспертиза лекарственных средств, 2023
Scientific relevance. When harmonising conditions for qualitative and quantitative analysis of bioactive compounds in herbal medicines, the Institute of Pharmacopoeia and Medicinal Product Standardisation has discovered that horse-chestnut products lack ...
O. V. Evdokimova, V. L. Bagirova, A. V. Beketova, M. N. Lyakina   +3 more
doaj   +1 more source

Development, certification, and use of a pharmacopoeial standard for the content of immunoglobulin A in human immunoglobulins for parenteral administration

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. The immunoglobulin A (IgA) impurity content in parenteral human immunoglobulins should be determined in accordance with the State Pharmacopoeia of the Russian Federation by kinetic nephelometry, radial immunodiffusion, or enzyme ...
A. V. Nechaev, E. Yu. Kudasheva, E. L. Postnova, R. A. Volkova, O. V. Fadeikina, I. V. Borisevich, A. A. Movsesyants   +6 more
doaj   +1 more source

Modification of the Method for the Determination of Zinc Content in Insulins by Atomic Absorption Spectrometry

Регуляторные исследования и экспертиза лекарственных средств, 2023
Scientific relevance. Zinc quantification in insulin active substances and preparations by atomic absorption spectrometry requires a sample preparation procedure using hydrochloric acid, a narcotic and psychotropic precursor.
A. A. Erina, V. M. Shchukin, E. A. Khorolskaya, N. E. Kuz'mina   +3 more
doaj   +1 more source

Development and validation of the quantitative determination procedure of iodine in the iodides form in the kelp thallus by the ionometry method

Journal of Pharmacy and Bioallied Sciences, 2020
Introduction: Iodine is an important compound in the kelp thallus; it should be determined to control the quality of crude herbal drugs of Laminaria sp.
Alexander V Nikulin, Olga G Potanina, Marina V Okuneva, Rimma A Abramovich, Dmitry O Bokov, Olga A Smyslova   +5 more
doaj   +1 more source

Development and Validation of an HPLC-DAD Analysis for Pharmacopoeial Qualification of Industrial Capsicum Extracts [PDF]

Journal of Chromatographic Science, 2014
A reverse-phase high-performance liquid chromatography method was developed to quantify capsaicin (trans-8-methyl-N-vanillyl-6-nonenamid), dihydrocapsaicin (8-methyl-N-vanillylnonanamide) and the main capsaicinoid contents of Capsicum extracts. The chromatographic separation was carried out on a C8 column using isocratic mobile phase consisting of 40% (
Mónika, Kuzma, Krisztina, Fodor, Borbála, Boros, Pál, Perjési   +3 more
openaire   +2 more sources

Development and validation of spectrophotometric procedure for quantitative determination of flavonoid content used to control the quality of mixture herbal product

Journal of Advanced Pharmaceutical Technology & Research, 2019
Species, known as mixture herbal products, are compositions of several types of crushed, sometimes whole, medicinal plant materials with additives; they are a widely used dosage form in the Russian Federation. A large range of species are produced at the
Olga Alekandrovna Smyslova, Dmitry Olegovich Bokov, Olga Georgievna Potanina, Tatyana Mikhailovna Litvinova, Irina Alexandrovna Samylina   +4 more
doaj   +1 more source

Modulation of Cox-1, 5-, 12- and 15-Lox by popular herbal remedies used in southern Italy against psoriasis and other skin diseases. [PDF]

, 2014
Acanthus mollis (Acanthaceae), Achillea ligustica, Artemisia arborescens and Inula viscosa (Asteraceae) are used in Southern Italy against psoriasis and other skin diseases that occur with an imbalanced production of eicosanoids.
Amenta, Ammon, Bader, Brand-Williams, Bremner, Bruni, Bruno, Charlier, Dehmlow, DiSepio, Flora, Glaser, Henke, Iversen, Luper, Mosmann, Pannala, Safayhi, Safayhi, Serhan, Spector, Sun, Tornhamre, Tzakou, Voorhees, Wang, Yamamoto   +26 more
core   +1 more source

A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products [PDF]

, 2013
Background: Artemisinin-based fixed dose combination (FDC) products are recommended by World Health Organization (WHO) as a first-line treatment. However, the current artemisinin FDC products, such as beta-artemether and lumefantrine, are inherently ...
Bracke, Nathalie, Burvenich, Christian, D'Hondt, Matthias, De Spiegeleer, Bart, Duchateau, Luc, Peremans, Kathelijne, Vandercruyssen, Kirsten, Wega, Sultan Suleman, Wynendaele, Evelien   +8 more
core   +2 more sources

ANALYSIS OF VIPAKA (METABOLIC TRANSFORMATION) OF AN EXTRA-PHARMACOPOEIAL DRUG-BRIDELIA STIPULARIS (L.) BLUME

International Journal of Pharmacy and Pharmaceutical Sciences, 2020
Objective: The objective of the present study is to explore the vipaka of an extra-pharmacopoeia drug Bridelia stipularis (L.) Blume belongs to the Euphorbiaceae family. Methods: 12 Wistar strain albino rats were selected and divided into 2 groups; Group A-Control, Group B-Test group.
HARITHA N, SUDHAKAR BHAT, N MANOJ KUMAR
openaire   +2 more sources